Search for dissertations about: "endogenous reference gene"

Showing result 1 - 5 of 16 swedish dissertations containing the words endogenous reference gene.

  2. 1. Effects of Biomechanical Stress on Gene Regulation in Vascular Cells

    Author : Maria Carlström; Göteborgs universitet; []
    Keywords : shear stress; intraluminal pressure; endothelium; gene expression; DNA microarray; real-time RT-PCR; reference genes; smooth muscle cells; P2 receptors; TNF-alpha; urokinase-type plasminogen activator;

    Abstract : The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. READ MORE

  4. 2. Effects of Endogenous and Exogenous Hormones on the Female Breast : With Special Reference to the Expression of Proteoglycans

    Author : Gunilla Hallberg; Tord Naessén; Gunvor Ekman-Ordeberg; Ingemar Persson; Cecilia Magnusson; Eva von Schoultz; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast tissue; proteoglycans; mammographic density; oral contraceptives; androgen receptor; proliferation; apoptosis; extracellular matrix; premenopausal; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : This thesis aims to study the effects of endogenous and exogenous hormones and mammographic breast density (BD) on cellular markers in non-cancerous female breast tissue. Women on the waiting list for breast reduction plastic surgery were recruited (n = 79), and randomized to 2 months of hormone therapy or no therapy before surgery. READ MORE

  5. 3. Experimental gene therapy with special reference to plasma cell tumors

    Author : M Sirac Dilber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Gene therapy may open new perspectives in the treatment of numerous hematopoietic and metabolic disorders. Particularly, hematopoietic cells are very attractive targets for retroviral mediated gene transfer. READ MORE

  6. 4. Studies on effects of antioxidants on arterial thrombosis and endothelial cell injury : With special reference to Tocopherols and ApoA1 Milano

    Author : Dayuan Li; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; tocopherols; apoA1 Milano; platelet aggregation; thrombosis; superoxide dismutase; nitric oxide synthase; endothelial cells; oxidized LDL; transcription factor; apoptosis; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

    Abstract : Coronary arterial endothelial injury and thrombosis are believed to be critical factors in the pathogenesis of coronary artery disease (CAD). Experimental studies have provided evidence for au inverse relation between acute coronary events and antioxidant intake. READ MORE

  7. 5. Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease : Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat

    Author : Eva Warensjö; Ulf Risérus; Bengt Vessby; Tommy Cederholm; David Laaksonen; Uppsala universitet; []
    Keywords : Nutrition; Fatty acids; Dietary fat; Biomarker; Metabolic Syndrome; Mortality; Obesity; Insulin Sensitivity; Epidemiology; Estimated desaturase activities; Stearoyl-CoA-desaturase; delta-6-desaturase; delta-5-desaturase; Single Nucleotide Polymorphism; Dietary Intervention; Rapeseed oil; Saturated fat; SCD1; Näringslära;

    Abstract : The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. READ MORE