Search for dissertations about: "endogenous retrovirus"

Showing result 1 - 5 of 19 swedish dissertations containing the words endogenous retrovirus.

  2. 1. Endogenous Retroviral RNA Expression in Humans

    Author : Lijuan Hu; Jonas Blomberg; Göran Friman; Francois Mallet; Uppsala universitet; []
    Keywords : Microbiology; Human endogenous retrovirus HERV ; HERVE; HERVW; betaretrovirus; gammaretrovirus; RNA expression; real time PCR; endometrium; endometriosis; brain tissue; reproductive tissue; ovarian cancer; ovary; neuroblastoma cell line; Mikrobiologi;

    Abstract : Human endogenous retroviruses (HERVs) constitute about 8% of the human genome. There are around 4000 pol-containing retroviral integrations in the human genome, which makes it impractical to measure each of them separately. READ MORE

  4. 2. Genomic Variation and Evolution of HERV-H and other Endogenous Retroviruses (ERVs)

    Author : Patric Jern; Jonas Blomberg; Michael Tristem; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Endogenous Retrovirus ERV ; HERV-H; Phylogeny; Evolution; Sequence Variation; Polymorphism; Recent Integrations; Horizontal Transfer; Master Elements; Taxonomy; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Abstract : An exogenous retrovirus (XRV) that integrates into a germ cell may be inherited as a Mendelian gene; it becomes an endogenous retrovirus (ERV). The human genome consists of up to 8% HERVs. The gammaretroviral (ERV class I) HERV-H, with 926 members, is the largest ERV group. READ MORE

  5. 3. Studies of human endogenous retroviruses and of the TGF-beta signaling pathway

    Author : Christian Kjellman; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; high-density filter array; gliom; TGF-beta; XA34; Human endogenous retrovirus; HERV-F; transplantation; serologi; Immunologi; serology; Immunology;

    Abstract : The human genome, in common with all mammalian genomes, carries a high load of inheritable retroviral sequences. We have identified and characterized a novel family of these endogenous retroviruses and have named this family HERV-F as based on the primer binding sites of three members. READ MORE

  6. 4. Transcription, splicing and genetic structure within the human endogenous retroviral HERV-H family

    Author : Mats Lindeskog; Institutionen för naturgeografi och ekosystemvetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; immunosuppressive envelope protein; RNA splicing; Human endogenous retrovirus; transcription; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Human endogenous retroviruses (HERVs) are remains of ancient retroviral infections of the germ line and constitute as much as 3 % of the human genome. HERVs are genetic elements that potentially may provide important biological functions by several different mechanisms. READ MORE

  7. 5. Human Endogenous Retroviruses: Studies on Transcriptional Activity and Genetic Variability

    Author : Patrik Medstrand; Malmö Klinisk virologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; virology; bacteriology; HERVs; Human endogenous retrovirus sequences; reverse transcriptase; Microbiology; differential RNA expression.; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Endogenous retroviruses (ERVs) are believed to be remains of germ-line infections that have become fixed in the population. They are involved in pathophysiological conditions, in mechanisms leading to infection protection, and directly in the physiology of the organism by participating in the regulation of cellular gene expression. READ MORE