Search for dissertations about: "energy metabolism enzymes"

Showing result 1 - 5 of 67 swedish dissertations containing the words energy metabolism enzymes.

  1. 1. Regulation of energy metabolism in tumor cells : the role of hexokinase

    Author : Firoz Kabir; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neoplasms; metabolism;

    Abstract : Changes in glucose metabolism are among the most universal andfundamental metabolic alterations observed in cancer cells. Hexokinase isthe initial regulatory enzyme which controls the rate of glucose entranceinto the glycolytic pathway. The content of hexokinase in tumor cells iselevated, and most of the enzyme is bound to mitochondria. READ MORE

  2. 2. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

    Author : Cecilie Mathiesen; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

    Abstract : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. READ MORE

  3. 3. Cyanobacterial Hydrogen Metabolism : Regulation and Maturation of Hydrogenases

    Author : Ellenor Devine; Peter Lindblad; Karin Stensjö; Laurent Cournac; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cyanobacteria; hydrogenase; hydrogenase specific protease; maturation; regulation; transcriptional studies; hupW; hoxW; hyp; NtcA; CalA; Biology; Biologi; Molecular biology; Molekylärbiologi; Microbiology; Mikrobiologi; Chemistry with specialization in Microbial Chemistry; Kemi med inriktning mot mikrobiell kemi;

    Abstract : In times with elevated CO2 levels and global warming there is a need of finding alternatives to carbon based energy carriers. One such environmental friendly solution could be H2 produced by living organisms. READ MORE

  4. 4. Heterogeneity of human metabolism in health and disease: a modelling perspective

    Author : Pouyan Ghaffari Nouran; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer metabolism; fatty acid metabolism; genome-scale metabolic models; community modeling; heterogeneity; lung cancer; amino acids metabolism; gut microbiome;

    Abstract : Metabolism is broadly defined as the sum of biochemical reactions within cells that are involved in maintaining the living state of the organism. Profound importance of metabolism comes from the fact that it is the sole source of energy that allows life to resist to be degraded into entropy. READ MORE

  5. 5. Adaptations and constraints associated with autotrophy in microbial metabolism

    Author : Johannes Asplund Samuelsson; Elton P. Hudson; Adil Mardinoglu; Costas D. Maranas; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Autotrophy; Carbon fixation; CO2 fixation; Calvin cycle; CBB cycle; Bacteria; Archaea; Prokaryotes; Cyanobacteria; Synechocystis; E. coli; Comparative genomics; Metabolic engineering; Microbial metabolism; Machine learning; Systems biology; Ribosome profiling; Kinetic modeling; Enzyme kinetics; Metabolic models; Pathway enumeration; Biosynthesis pathways; Metabolomics; Metabolite concentrations; Thermodynamics; Autotrofi; Kolfixering; CO2-fixering; Calvincykeln; CBB-cykeln; Bakterier; Arkéer; Prokaryoter; Cyanobakterier; Synechocystis; E. coli; Jämförande genomik; Metabolisk ingenjörskonst; Mikrobiell metabolism; Maskininlärning; Systembiologi; Ribosomprofilering; Kinetisk modellering; Enzymkinetik; Metaboliska modeller; Syntesvägsuppräkning; Biosyntesvägar; Metabolomik; Metabolitkoncentrationer; Termodynamik; Bioteknologi; Biotechnology;

    Abstract : Carbon dioxide (CO2) emissions from human activities are driving climate change, but the pending crisis could be mitigated by a circular carbon economy where released CO2 is recycled into commodity chemicals. Autotrophic microbes can make a contribution by producing chemicals, such as biofuels, from CO2 and renewable energy. READ MORE