Search for dissertations about: "enterohepatic circulation"

Showing result 6 - 10 of 13 swedish dissertations containing the words enterohepatic circulation.

  2. 6. On the detection and management of urinary bladder carcinoma

    Author : Andreas Thorstenson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aims: To describe the diagnosis and clinical course of an unselected population-based cohort of patients with newly diagnosed transitional cell carcinoma of the urinary bladder. To assess if random bladder biopsies and the detection of concomitant carcinoma in situ have an impact on management and clinical outcome in bladder cancer patients. READ MORE

  4. 7. Bile acid metabolism in humans : regulation of synthesis and circadian rhythms

    Author : Amani Al-Khaifi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Interfering with bile acids (BAs) signaling within the enterohepatic circulation (EHC) has recently emerged as an important way of controlling human metabolic homeostasis. This is highly relevant to a number of frequent disease entities such as dyslipidemia, fatty liver disease, insulin resistance, obesity, type 2 diabetes, gallstone disease and BA-induced diarrhea. READ MORE

  5. 8. On the regulation of hepatic cholesterol and bile acid metabolism in gallstone patients

    Author : Carl-Gustaf Hillebrant; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bile acid synthesis; biliary lipids; cholesterol synthesis; cholesterol 7a-hydroxylase; cholesterol synthesis inhibitor; chenodeoxycholic acid; cholestyramine; 7a-hydroxy-4-cholesten-3-one; HMG CoA reductase; lathosterol; lipoproteins; lithocholic acid; plasma apheresis; ursodeoxycholic acid;

    Abstract : The liver plays an important role in the regulation of cholesterol homeostasis, therefore also in the pathogenesis of arteriosclerosis and gallstone disease. The quantitatively most important way by which cholesterol is removed from the human body is via the bile, either as free cholesterol or after transformation to bile acids. READ MORE

  6. 9. Studies on the hormonal regulation of bile acid synthesis

    Author : Thomas Lundåsen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The maintenance of a normal turnover of cholesterol is of vital importance, and disturbances of cholesterol metabolism may result in several important disease conditions. The major route for the elimination of cholesterol from the body is by hepatic secretion of cholesterol and bile acids (BAs) into the bile for subsequent fecal excretion. READ MORE

  7. 10. Studies on cholesterol and lipoprotein metabolism : emphasis on diabetes and sugar

    Author : Johanna Apro; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cholesterol has important functions in the body; as a precursor in the synthesis of steroid hormones and bile acids (BAs), and as a component of cellular membranes. However, an elevated level of plasma cholesterol, transported in low density lipoprotein (LDL) particles, is one of the major risk factors and causes for cardiovascular disease. READ MORE