Search for dissertations about: "enterotoxigenic E. coli"

Showing result 1 - 5 of 17 swedish dissertations containing the words enterotoxigenic E. coli.

2. 1. Structural analyses of carbohydrate receptors for enterotoxins and adhesins of enterotoxigenic Escherichia coli

   Author : Dani Zalem; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carbohydrate recognition; glycosphingolipid; diarrheagenic E. coli; ETEC; heat-labile enterotoxin; colonization factor; AB5 toxins;

   Abstract : Carbohydrate-binding proteins expressed by microbes are key determinants in initiating and sustaining infections that account for millions of deaths each year. This thesis fo- cused on proteins integral to infections instigated by enterotoxigenic Escherichia coli (ETEC); estimated as the largest bacterial cause of diarrhea in the world with hundreds of millions of cases each year. READ MORE

4. 2. Whole Genome Sequencing of Enterotoxigenic Escherichia coli

   Author : Astrid von Mentzer; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ETEC; whole genome sequencing; evolution; colonization factor; reverse genetics;

   Abstract : Enterotoxigenic Escherichia coli (ETEC) infections are a common cause of diarrhea but little is known about the evolution and genomic composition of ETEC. The main aim of this thesis was to generate a large collection of whole genome sequenced ETEC isolates to study the evolution of such bacteria on a global level and to search for novel colonization factors (CFs) using both classical and cutting-edge genomic techniques. READ MORE

5. 3. Studies of Carbohydrate-Binding Proteins from Enterotoxigenic Escherichia coli

   Author : Lena Jansson; Göteborgs universitet; []
   Keywords : Carbohydrate recognition; ETEC colonization factors; CFA I fimbriae; CS6 protein; heat-labile enterotoxin;

   Abstract : Knowledge about the carbohydrate binding specificity of pathogens can give an increased understanding of their virulence strategies, and is also of importance for the development of anti-adhesive therapies and vaccines. Enterotoxigenic Escherichia coli (ETEC) is a well-known causative agent of diarrheal disease. READ MORE

6. 4. Studies on bacterial transmission pathways in a high endemic area, with a focus on Helicobacter pylori

   Author : Anders Janzon; Göteborgs universitet; []
   Keywords : H. pylori; enterotoxigenic E. coli; V. cholerae; real-time PCR; transmission pathways; gastroenteritis; mouse infection models; bacterial gene expression;

   Abstract : Even though half of the world’s population is infected with Helicobacter pylori, which causes gastritis, peptic ulcer and gastric cancer, the transmission routes of these bacteria remain unknown despite extensive epidemiological studies. Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae are two of the most common causes of acute watery diarrhea in developing countries. READ MORE

7. 5. Studies on the Expression and Regulation of Enterotoxins and Colonization Factors in Enterotoxigenic Escherichia coli (ETEC)

   Author : Matilda Nicklasson; Göteborgs universitet; []
   Keywords : ETEC; heat-stable enterotoxin; heat-labile enterotoxin; colonization factors; CS5; CS6; virulence gene expression; in vivo and in vitro; genetic variability;

   Abstract : Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of acute watery diarrhoea in developing countries, particularly among local children less than five years and is also the most common cause of diarrhoea in travellers to ETEC endemic areas. The infection is transmitted by ingestion of contaminated food and water and the disease is established in the small intestine. READ MORE