Search for dissertations about: "enzymatic regulation"

Showing result 1 - 5 of 107 swedish dissertations containing the words enzymatic regulation.

  2. 1. Enzymatic Regulation of Steroidogenesis and Nuclear Receptor Activation : Special Focus on Vitamin D and Sex Hormones

    Author : Johan Lundqvist; Kjell Wikvall; Maria Norlin; Magnus Ingelman-Sundberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adrenal steroidogenesis; CYP7B1; vitamin D; calcitriol; enzymatic regulation; transcriptional regulation; CYP21A2; aromatase; sex hormone; estrogen; androgen; nuclear receptor; Pharmaceutical biochemistry; Farmaceutisk biokemi; Farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : Enzyme-catalyzed reactions are important to regulate steroidogenesis and nuclear receptor activation. The present investigation examines the role of steroid metabolism catalyzed by CYP7B1 for regulation of hormone receptor activation and the effects of vitamin D on enzymatic regulation of steroidogenesis. READ MORE

  4. 2. Tripeptidyl-Peptidase II : Structure, Function and Gene Regulation

    Author : Ann-Christin Lindås; Birgitta Tomkinson; Mikael Widersten; Ralf Morgenstern; Uppsala universitet; []
    Keywords : Biochemistry; gene regulation; protein expression; enzyme kinetics; tripeptidyl-peptidase II; proteasome; intracellular protein degradation; exopeptidase; Biokemi;

    Abstract : The protein degradation process is of vital importance for the cell to maintain cellular functions. An important enzyme in this process is the multimeric tripeptidyl-peptidase II (TPP II). It removes tripeptides from a free N-terminus of the substrates. READ MORE

  5. 3. Violaxanthin De-epoxidase and the Xanthophyll Cycle

    Author : Anna Gisselsson; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plant biochemistry; zeaxanthin.; xanthophyll cycle; violaxanthin de-epoxidse; thylakoid; regulation; quenching; protonation; pH-dependence; light stress; histidine; Conformational change; domains; Växtbiokemi;

    Abstract : The xanthophyll cycle is a mechanism for short term adaptation of plants to varying light intensities. It involves a reversible conversion of violaxanthin to zeaxanthin, via the intermediate antheraxanthin, upon high light intensities. READ MORE

  6. 4. Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex

    Author : Cecilia Boreström; Göteborgs universitet; []
    Keywords : Epstein-Barr virus; EBNA1; NF-Y; Sp1; Oct-2; Bright; E2F1; transcriptional regulation; Cp; oriP;

    Abstract : Epstein-Barr Virus (EBV) is an exclusively human, lymphotropic herpes virus that infects more than 90% of the population worldwide. Primary infection usually occurs during the early years of life and does not result in any recognized disease. READ MORE

  7. 5. The enzymatic machinery of leukotriene biosynthesis : Studies on ontogenic expression, interactions and function

    Author : Tobias Strid; Sven Hammarström; Mats Söderström; Ralf Morgenstern; Linköpings universitet; []
    Keywords : ;

    Abstract : Leukotrienes (LTs) are biologically active arachidonic acid (AA) derivatives generated by the 5-lipoxygenase (5-LO) pathway. They are produced by myeloid cells. 5-LO converts AA to LTA4 in cooperation with 5-LO activating protein (FLAP). LTA4 is converted to LTB4, by LTA4-hydrolase (LTA4H) or to LTC4 by LTC4-synthase (LTC4S). READ MORE