Search for dissertations about: "epidermal growth factor receptors"

Showing result 1 - 5 of 61 swedish dissertations containing the words epidermal growth factor receptors.

2. 1. Receptors for growth hormone and prolactin. Regulation and activation

   Author : Gunnel Hellgren; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; GH receptor; Janus kinase; GH sensitivity; 5 -untranslated region; prolactin; prolactin receptor adipose tissue; liver; skeletal muscle; epidermal growth factor receptor; tyrosine kinase; kinase activity;

   Abstract : Cytokine receptor activation is dependent on ligand-induced receptor dimerization or oligomerization and subsequent activation of several intracellular proteins. Activation of Janus kinases (Jaks) is probably the first intracellular event that occurs after receptor dimerization. READ MORE

4. 2. Current Medical Treatment of Endocrine Pancreatic Tumors and Future Aspects

   Author : Marie-Louise Fjällskog; Morten Vatn; Uppsala universitet; []
   Keywords : Medical sciences; pancreatic tumors; somatostatin analogs; cisplatin; etoposide; somatostatin receptors; immunohistochemistry; tyrosine kinase receptors; platelet-derived growth factors receptors PDGFRs ; c-kit; epidermal growth factor receptor EGFR ; MEDICIN OCH VÅRD; alfa-interferon; MEDICINE; MEDICIN; Medicine; medicin;

   Abstract : We treated 16 patients with somatostatin analogs combined with α-interferon and achieved a biochemical and/or radiological response in 56% (median duration 22 months). We consider this treatment a good alternative for patients who fail during chemotherapy or who do not want to/cannot receive cytotoxic drugs. READ MORE

5. 3. Dynamics and gene expression of growth factor receptors in human cultured skin cells : Effects of UV radiation and calcium on EGF- and PDGF-receptors

   Author : Margareta Lirvall; Gunnar Kratz; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : Growth factors transmit biological signals for the stimulation of cell growth and their stimulation may be involved in turnourigenesis. It is therefore of great importance to understand growth factor receptor reactions in response to stimuli such as calcium depletion or ultraviolet radiation, which normal human cells are invariably exposed to during their growth cycle. READ MORE

6. 4. Targeting Human Epidermal Growth Factor Receptors with Drug Conjugates Based on Affibody Molecules

   Author : Jie Zhang; Torbjörn Gräslund; Per-Åke Nygren; Marika Nestor; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Affibody molecule; HER2; HER3; affibody-drug conjugate; half-life; payload; Affibody-molekyl; HER2; HER3; affibody-läkemedelskonjugat; halveringstid; nyttolast; Biotechnology; Bioteknologi;

   Abstract : Cancer is a major public health challenge and the second leading cause of death in the world, with millions of new cases being diagnosed each year. Traditional cancer treatments such as surgery, radiation therapy, and chemotherapy are many times effective, but may also cause damage to healthy cells, leading to side effects. READ MORE

7. 5. Midgut Carcinoid Tumours : New Diagnostic Procedures and Treatment

   Author : Staffan Welin; Eva T. Janson; Barbro Eriksson; Larry Kvols; Uppsala universitet; []
   Keywords : Medicine; Midgut carcinoid tumour; Chromogranin A; Carcinoid heart disease; Survival; Octreotide pamoate; Tyrosine kinase receptors; Platelet derived growth factor receptor; Epidermal growth factor receptor; Medicin;

   Abstract : Midgut carcinoid tumours are rare with an incidence of 0.5-2.1/100 000. The primary tumour is usually small and grows slowly but has almost always set metastases at diagnosis. READ MORE