Search for dissertations about: "epidermis"

Showing result 21 - 25 of 115 swedish dissertations containing the word epidermis.

  2. 21. Understanding the role of non-coding RNAs in skin homeostasis and cancer

    Author : Kunal Das Mahapatra; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The epidermis is a stratified epithelium with continuous self-renewing capacity. As the outermost layer of our body, it provides a protective barrier against external trauma, produces pigmentation, and keeps the skin hydrated. Keratinocytes are the primary constituent cells type within the epidermis. READ MORE

  4. 22. Epidermal stem cells at the point of no return

    Author : Karl Annusver; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The skin is our main barrier against outside harm, and it helps to maintain internal homeostasis. These functions are mostly fulfilled by the epidermis, which is the outermost layer of the skin, formed from keratinocytes that are constantly being shed and replaced through proliferation, differentiation, and subsequent delamination of tissue resident stem cells. READ MORE

  5. 23. Mechanisms of resident T cell-driven tissue responses during the onset and recurrence of human skin inflammation

    Author : Irène Gallais Sérézal; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Long-lived tissue-resident memory T cells (TRM) reside in nonlymphoid organs and can drive direct cytotoxicity, focal cytokine release and potent tissue-wide anti-infectious responses upon antigenic challenge. TRM cells poised to pathogenic responses have been identified in active and resolved psoriasis and mice models of allergic contact dermatitis (ACD). READ MORE

  6. 24. Deciphering the complexity of psoriasis : non-coding RNAs and cellular interactions

    Author : Longlong Luo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Psoriasis is a prevalent immune-mediated skin disorder marked by chronically relapsing inflammation and epidermal hyperproliferation. As researchers delve deeper into the molecular intricacies of psoriasis, emerging evidence hints at the roles of non-coding RNAs (ncRNAs). READ MORE

  7. 25. Compartmentalisation of the immune response in human skin : cross-talk between dendritic cells and T cells in healthy conditions and in psoriasis

    Author : Elisa Martini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human skin is highly compartmentalised and distinct subsets of dendritic cells (DCs) and T cells reside in epidermis and dermis. Alterations in the composition of DCs and T cells have been observed in psoriasis, a common cytokine-driven focal inflammatory skin disease. READ MORE