Search for dissertations about: "epigenetic inheritance"

Showing result 1 - 5 of 16 swedish dissertations containing the words epigenetic inheritance.

  2. 1. Stress and the Offspring : Adaptive Transgenerational Effects of Unpredictability on Behaviour and Gene Expression in Chickens (Gallus gallus)

    Author : Daniel Nätt; Per Jensen; Berry Spruijt; Linköpings universitet; []
    Keywords : Chicken; Red junglefowl; Domestication; Epigenetics; Transgenerational; Inheritance; Gene expression; Microarray; qRT-PCR; Immunogenetics; Immunoglobulin; Estradiol; Steriod hormones; Prenatal stress; Epigenetic inheritance; Adaptation; Stress; Behaviour; Ethology of domestic animals; Husdjurens etologi;

    Abstract : Environmental stress has shown to affect both the exposed individuals and the development of their offspring. Generally, it is thought that the stressed organism responds to stress by trying to adapt to it. READ MORE

  4. 2. Inheritance of autoimmune neuroinflammation

    Author : Pernilla Stridh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic neuro-inflammatory disease with anticipated complex etiology. Susceptibility to MS is conferred by numerous genes, with very low odds ratios that explain minute fractions of disease. This indicates that unknown factors are responsible for the remaining genetic contribution, termed the missing heritability. READ MORE

  5. 3. Heritable epigenetic responses to environmental challenges : Effects on behaviour, gene expression and DNA-methylation in the chicken

    Author : Daniel Nätt; Per Jensen; Adroaldo Zanella; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Phenotypic variation within populations is a crucial factor in evolution and is mainly thought to be driven by heritable changes in the base sequence of DNA. Among our domesticated species we find some of the most variable species on earth today. READ MORE

  6. 4. Epigenetic Regulation of the H19 Chromatin Insulator in Development and Disease

    Author : Claes Holmgren; Rolf Ohlsson; Tomas Ekstöm; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Developmental Biology; Miljömedicinsk utvecklingsbiologi;

    Abstract : The coordinated regulation of gene expression must be tightly controlled for normal development to occur. In mammals, this issue is further complicated by the requirement of both the maternal and paternal genomes for normal development, reflecting the fact that a subset of genes are monoallelically expressed depending on parental inheritance, a phenomenon known as genomic imprinting. READ MORE

  7. 5. Involvement of epigenetic mechanisms in disease inheritance and pathogenesis of multiple sclerosis (MS) with a focus on genomic imprinting and DNA methylation in CD4+ T cells

    Author : Sabrina Ruhrmann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative disease driven by autoreactive CD4+ T cells. Disease etiology is mediated by a strong interplay between genetic and environmental factors implying a role for epigenetic mechanisms. READ MORE