Search for dissertations about: "epigenetics"

Showing result 1 - 5 of 85 swedish dissertations containing the word epigenetics.

  1. 1. Networks in epigenetics

    Author : Kuljeet Sandhu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Networks are ubiquitous. It is only recently, we started exploring what purpose they serve in real world. Biological research supposedly has, and will be, benefited most from the network science because of inherent complexity embedded in its multilayered organization. READ MORE

  2. 2. On the role of genetic variation and epigenetics in hemostatic gene regulation

    Author : Martina Olsson Lindvall; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hemostasis; Tissue-type plasminogen activator; Genetics; Epigenetics; DNA methylation;

    Abstract : Many genetic variants have been identified to associate with circulating levels of hemostatic proteins and with thrombotic or hemorrhagic disorders. However, the underlying molecular mechanisms remain largely unknown. READ MORE

  3. 3. Epigenetics of paediatric glioma stem cells; focusing on exosomes, miRNAs and DNA methylation

    Author : Ágota Tüzesi; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; microRNA; DNA methylation; exosomes; glioblastoma; paediatric; glioma stem cells; neural stem cells; TMZ response;

    Abstract : Tumours in the central nervous system are accountable for the majority of cancer-related deaths in children. Glioblastoma multiforme, one of the deadliest of the central nervous system tumours, is partly driven by glioma stem cells. The generation and maintenance of these cells is orchestrated by complex genetic and epigenetic mechanisms. READ MORE

  4. 4. Epigenetics in nasopharyngeal carcinoma

    Author : Di Sun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NPC; Methylation; TSG; EBV; LMP1; CDH13; RASSF2A; MMSP;

    Abstract : Nasopharyngeal carcinoma (NPC) shows a remarkably distinctive ethnic and geographic distribution among the world suggesting that genetic susceptibility backgrounds cooperate with the environmental risk factors in etiology of NPCs. Among the environmental factors, much attention has been focused on a well-documented association with Epstein-Barr virus (EBV), which can be detected in 100% undifferentiated NPCs. READ MORE

  5. 5. Epigenetic and Phenotypic Profiling of Urothelial Carcinoma

    Author : Mattias Aine; Bröstca-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; DNA methylation; gene expression; urothelial carcinoma; bladder cancer;

    Abstract : Precise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. READ MORE