Search for dissertations about: "epigenetics"

Showing result 1 - 5 of 79 swedish dissertations containing the word epigenetics.

  1. 1. The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes

    University dissertation from Epigenetics and Diabetes

    Author : Tasnim Dayeh; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CpG-SNP; glucagon secretion; insulin secretion; human pancreatic islets; DNA methylation; Epigenetics;

    Abstract : Islet dysfunction is central to the development and progression of type 2 diabetes (T2D). Epigenetic modifications are essential for establishing and maintaining cell identity and function in normal circumstances. Exposure to adverse environmental factors may alter the epigenome, and result in changes of gene expression and the resulting phenotype. READ MORE

  2. 2. Study of DNA methylation in human pancreatic islets

    University dissertation from Epigenetics and Diabetes

    Author : Elin Hall; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; epigenetics; DNA mehtylation; human pancreatic islets; insulin secretion;

    Abstract : Today type 2 diabetes is a common disease with a worldwide prevalence of 8.3%. The disease is characterised by hyperglycaemia which is a result of insufficient insulin secretion from the beta-cells in the pancreatic islets as well as an insulin resistance seen in the target tissues. READ MORE

  3. 3. Genetic and epigenetic influence on oxidative phosphorylation, islet function and type 2 diabetes in humans

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Anders H Olsson; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Genetics; Epigenetics; Human Pancreatic Islets; Oxidative Phosphorylation; Insulin Secretion;

    Abstract : The prevalence of type 2 diabetes (T2D) is increasing worldwide. T2D is a heterogeneous disease caused by a complex interplay between multiple genetic, epigenetic and non-genetic factors. The disease is characterised by impaired insulin secretion from pancreatic β-cells and insulin resistance in peripheral tissues. READ MORE

  4. 4. Genome-wide analysis of the DNA methylation landscape in human tissues

    University dissertation from Lund University: Faculty of Medicine

    Author : Petr Volkov; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bioinformatics; epigenetics;

    Abstract : .... READ MORE

  5. 5. Non-invasive Rejection Surveillance after Heart Transplantation

    University dissertation from Lund University: Faculty of Medicine

    Author : Ihdina Sukma Dewi; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [2017]
    Keywords : ;

    Abstract : .... READ MORE