Search for dissertations about: "epigenetics"
Showing result 16 - 20 of 111 swedish dissertations containing the word epigenetics.
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16. Overlapping Neural Substrates of Alcohol- and Anxiety-Related Behavior in the Rat
Abstract : Alcohol use is a leading cause of death and disease worldwide. A large part of this disease burden is associated with alcohol use disorder (AUD), a diagnostic category characterized by excessive use in spite of negative consequences ("compulsive use"), a loss of control over intake, and choice of alcohol over natural rewards. READ MORE
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17. Epigenetic Dysregulations in the Brain of Human Alcoholics : Analysis of Opioid Genes
Abstract : Neuropeptides are special in their expression profiles restricted to neuronal subpopulations and low tissue mRNA levels. Genetic, epigenetic and transcriptional mechanisms that define spatiotemporal expression of the neuropeptide genes have utmost importance for the formation and functions of neural circuits in normal and pathological human brain. READ MORE
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18. The role of nuclear envelope proteins in chromatin organization, differentiation and disease
Abstract : In eukaryotes the genetic material is separated from the cytoplasm by the nuclear envelope (NE), consisting of the outer and inner nuclear membrane, the nuclear lamina and the nuclear pores. The genetic material is highly structured with transcriptionally inactive heterochromatin enriched at the nuclear periphery and transcriptionally active euchromatin in the nuclear interior. READ MORE
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19. The role of nuclear membrane proteins in differentiation and chromatin organization
Abstract : The nuclear envelope, consisting of an outer and an inner nuclear membrane, surrounds the genomic material. The genomic material (chromatin) is highly structured with (transcriptionally inactive) heterochromatin mostly found in the nuclear periphery and (transcriptionally active) euchromatin mostly found in the nuclear interior. READ MORE
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20. Epigenetic Regulation of Replication Timing and Signal Transduction
Abstract : Upon fertilization the paternal and maternal genomes unite, giving rise to the embryo, with its unique genetic code. All cells in the human body are derived from the fertilized ovum: hence they all contain (with a few exceptions) the same genetic composition. READ MORE