Search for dissertations about: "epilepsy"

Showing result 16 - 20 of 165 swedish dissertations containing the word epilepsy.

  1. 16. Mechanisms of excitability in the central and peripheral nervous systems Implications for epilepsy and chronic pain

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Jenny Tigerholm; KTH.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dendritic excitability; synchronized synaptic input; multicompartment model; epilepsy; axonal excitability; silent C–fibres; Hodgkin–Huxley dynamics; conduction velocity; KA;

    Abstract : The work in this thesis concerns mechanisms of excitability of neurons. Specifically, it deals with how neurons respond to input, and how their response is controlled by ion channels and other active components of the neuron. READ MORE

  2. 17. Radiological Studies on Hippocampal Development Morphological Variants and their Relationship to Epilepsy

    University dissertation from Uppsala : Institutionen för onkologi, radiologi och klinisk immunologi, Enheten för radiologi

    Author : Dragan Bajic; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MRI; Brain development; Hippocampus; Epilepsy; MEDICINE Physiology and pharmacology Radiological research Radiology; MEDICIN Fysiologi och farmakologi Radiologisk forskning Radiologi; Radiology; Radiologi;

    Abstract : During fetal development, the hippocampal structures are folded forming the hippocampal sulcus which penetrates into the temporal lobe and then the entity rotates.  During this process, the hippocampal sulcus will be closed and the inverted hippocampus takes a rounded form. READ MORE

  3. 18. 201Thallium SPECT; accuracy in astrocytoma diagnosis and treatment evaluation

    University dissertation from Uppsala : Institutionen för onkologi, radiologi och klinisk immunologi, Enheten för radiologi

    Author : Kristina Källén; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; Lunds universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The aims of the studies included in this thesis were:• to investigate the reliability of 201thallium single photon emission computed tomography (201Tl SPECT) for preoperative diagnosis and histological staging of malignant astrocytomas in comparison with CT; • to develop a method for quantification of cerebral thallium uptake, and to evaluate the quantitative measurement in comparison with CT, for astrocytoma treatment follow-up purposes; • to compare quantitative 201Tl SPECT and proton magnetic resonance spectroscopy (1H-MRS) with conventional MR imaging for astrocytoma monitoring, and to evaluate associations between change of morphological tumour characteristics during treatment and changes of cerebral thallium uptake and metabolic ratios. Results and conclusions:• High 201Tl-index, calculated as a ratio comparing tumour uptake to uptake in the contralateral hemisphere, is an indicator of highly malignant astrocytoma. READ MORE

  4. 19. Gene therapy in epilepsy: neuropeptides and neurotrophic factors

    University dissertation from Section of Restorative Neurology, Division of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden

    Author : Irene Kanter Schlifke; Lund University.; Lunds universitet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; piriform cortex; hippocampus; neuropsykologi; encapsulated cells; viral vectors; GDNF; galanin; epilepsy; gene therapy; neurofysiologi;

    Abstract : Temporal lobe epilepsy (TLE) is the most common form of epilepsy among adult patients, and the most problematic one as seizures cannot be controlled by currently available drugs in 30 % of patients. Gene therapy based on overexpression of endogenous anti-epileptic agents such as the neuropeptide galanin and the glial cell line-derived neurotrophic factor (GDNF) represents a promising new approach for treatment of TLE. READ MORE

  5. 20. Brain Inflammation and Adult Hippocampal Neurogenesis in Epilepsy

    University dissertation from Neurology, Lund

    Author : Deepti Chugh; Lund University.; Lunds universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Inflammation; Neurogenesis; Hippocampus; Microglia; Adhesion molecules; Scaffolding proteins;

    Abstract : Epilepsy is a severe chronic neurological disorder characterized by recurrent spontaneous seizures. Excitatory/inhibitory (E/I) imbalance, neuronal loss, brain inflammation, and altered adult neurogenesis are some of the characteristic hallmarks of epilepsy. READ MORE