Search for dissertations about: "epimerisation"

Found 5 swedish dissertations containing the word epimerisation.

  2. 1. Enzymes as catalysts in synthesis of enantiomerically pure building blocks : secondary alcohols bearing two vicinal stereocenters

    Author : Rong Liu; Hans-Erik Högberg; Torbjörn Norin; Thorleif Anthonsen; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme; kinetic resolution; enantioselectivity; lipase; diastereoselectivity; epimerisation; metal-catalysed transformation; intramolecular alkylation.; Chemistry; Kemi;

    Abstract : Enzymes as tools in organic synthesis have provided enormous advantages. This thesis deals with the applications of enzymes in the kinetic resolutions of racemic compounds. The stereochemistry of chiral compounds and the kinetics of α/β hydrolase lipases are presented. READ MORE

  4. 2. Synthesis of Carbohydrate Mimics and Development of a Carbohydrate Epimerisation Method

    Author : Clinton Ramstadius; Ian Cumpstey; Robert Madsen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate Mimic; Ring-closing Metathesis; Carbohydrate Chemistry; Carbasugar; Aminocarbasugar; Pseudodisaccharide; Glycosidase and Lectin Inhibitors; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Abstract : In this thesis the synthesis of several hydrolytically stable carbohydrate mimics with the potential to function as glycosidase or lectin inhibitors are described. This work is presented in Chapters 2-5. READ MORE

  5. 3. The synthesis of three disaccharides, two methyl ethers of mannose and some epimerisation reactions

    Author : Gunnel Alfredsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : .... READ MORE

  6. 4. Progesterone metabolites : learning, tolerance, antagonism & metabolism

    Author : Charlotte Öfverman; Inga-Maj Johansson; Torbjörn Bäckström; Esa Korpi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allopregnanolone; isoallopregnanolone; THDOC; learning; tolerance; antagonism; inhibition; patch clamp; Morris water maze; metabolism; epimerization; Obstetrics and gynaecology; Obstetrik och gynekologi; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Progesterone metabolites as allopregnanolone, isoallopregnanolone and tetrahydrodeoxy-corticosterone (THDOC) are increased in the luteal phase of the menstrual cycle, throughout pregnancy and during stress. Allopregnanolone and THDOC are neurosteroids with 3α-hydroxy, 5α-configurations and positive modulating effect on the GABAA receptor. READ MORE

  7. 5. FROM GENE TO STRUCTURE: Formation of Iduronic Acid in Dermatan Sulfate by Two DS-epimerases

    Author : Benny Pacheco; Matrixbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : During embryonic development and adult life a wide range of cell behaviors such as differentiation, proliferation and migration are in effect to maintain tissue integrity and function. An integral part of these dynamic processes is the interplay between the cells and their environment, i.e. the extracellular space. READ MORE