Search for dissertations about: "epithelial electrical resistance"

Showing result 1 - 5 of 14 swedish dissertations containing the words epithelial electrical resistance.

  2. 1. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers

    Author : Staffan Tavelin; Per Artursson; Staffan Tavelin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; intestinal epithelium; tight junctions; cell culture; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. READ MORE

  4. 2. The Renin Angiotensin System in the Human Esophageal Mucosa − expression, actions and potential involvement in reflux disease

    Author : Eleonora Björkman; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endoscopic biopsies; epithelial electrical current; epithelial electrical resistance; esophageal mucosae; gastroesophageal reflux disease; mucosal barrier integrity; renin angiotensin system;

    Abstract : The renin angiotensin system (RAS) is a classical endocrine system, regulating body fluid balance and blood circulation. Recent research has shown that the system is being also locally expressed and active in several organs and tissues. READ MORE

  5. 3. Epithelial barrier dysfunction in ileal Crohn's disease

    Author : Johan Dabrosin-Söderholm; Svante Nordgren; Linköpings universitet; []
    Keywords : acetylsalicylic add; confocal microscopy; Crohn s disease; cytoskeleton; electron microscopy; genetics; human; ileum; inflammatory bowel disease; intestinal absorption; intestinal mucosa; macromolecules; mitochondria; ovalbumin; permeability; sodium caprate; tight junctions; transcytosis; uncoupling agents; Ussing chamber; MEDICINE; MEDICIN;

    Abstract : The study aimed at investigating the intestinal barrier in Crohn's disease, with special reference to epithelial responses to luminal stimuli, and to permeation of proteins.Ileal mucosa from patients undergoing intestinal resection was studied in vitro in Ussing chambers. READ MORE

  6. 4. On the Regulation of the Epithelial Paracellular Permeability

    Author : Pia Nybom; Janove Sehlin; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The epithelia of for instance the small intestine(s) plays a crucial role in the vectorial transport of nutrients and other solutes from the lumen to underlying body fluids, i.e. blood and lymph. READ MORE

  7. 5. Studies on CAR and CLMP : two proteins of epithelial tight junctions

    Author : Elisabeth Raschperger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Tight junctions are important structures for the function of epithelial cells. They are composed of multi-protein complexes that connect the plasma membranes of two adjacent epithelial cells to each other and function as paracellular barriers, which regulate flux of ions, solutes, proteins and cells across the epithelium. READ MORE