Search for dissertations about: "epithelial sodium channel ENaC"

Found 5 swedish dissertations containing the words epithelial sodium channel ENaC.

  2. 1. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism

    Author : Charlotta Schaedel; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pseudohypoaldosteronism type 1; cystic fibrosis transmembrane conductance regulator CFTR ; Cystic fibrosis; pulmonary disorder; Pediatrics; epithelial sodium channel ENaC; Pediatri;

    Abstract : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. READ MORE

  4. 2. Genetic factors in primary hypertension- with emphasis on renal sodium reabsorption

    Author : Olle Melander; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; diabetology; secreting systems; Endocrinology; alpha-adducin; Gitelman´s syndrome; Liddle´s syndrome; insulin resistance; genetics; intrauterine growth; salt sensitivity; Primary hypertension; essential hypertension; sekretion; diabetologi; Cardiovascular system; Kardiovaskulära systemet;

    Abstract : Genetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. READ MORE

  5. 3. Development and regulation of alveolar fluid clearance in the guinea pig

    Author : Andreas Norlin; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxytocin-induced preterm labor; IRDS; fetal lung fluid; preterm lung development; amiloride-sensitive sodium channels; beta-adrenergic stimulation; alveolar epithelium; Animal physiology; Djurfysiologi;

    Abstract : Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. READ MORE

  6. 4. Studies of Tight Junctions and Airway Surface Liquid in Airway Epithelium with Relevance to Cystic Fibrosis

    Author : Harriet Nilsson; Godfried M Roomans; Anca Dragomir; Marie Johannesson; Olafur Baldurson; Uppsala universitet; []
    Keywords : ;

    Abstract : Cystic fibrosis (CF) is a multi-organ autosomal recessive disease of fluid-transporting epithelia, due to a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CFTR is a cAMP-regulated Cl-channel involved in various regulatory processes. READ MORE

  7. 5. Role of ion and water channels for lung growth in congenital diaphragmatic hernia

    Author : Andreas Ringman Uggla; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Early lung development is based on a continuous cross-talk of growth and transcription factors between the developing lung bud and the surrounding parenchyma. Throughout fetal life, pulmonary growth and differentiation depend on Cl- driven lung liquid secretion. READ MORE