Search for dissertations about: "epoxide rearrangement"
Showing result 1 - 5 of 6 swedish dissertations containing the words epoxide rearrangement.
-
1. Development of New Chiral Bicyclic Ligands : Applications in Catalytic Asymmetric Transfer Hydrogenation, Epoxidations, and Epoxide Rearrangements
Abstract : This thesis describes the synthesis and application of new chiral bicyclic ligands and their application in asymmetric catalysis. The studies involved: [i] The development of novel chiral bicyclic amino sulfur ligands and their use in transfer hydrogenation. READ MORE
-
2. Synthesis and Rearrangement of Epoxy Sugars
Abstract : Ring-Contraction of sugar-derived epoxy alcohols, functionalised in position 1 and 6, by treatment with lithium bromide and N, N, N', N'-tetramethylurea in refluxing toluene gave enantiomerically pure a,b-unsaturated aldehydes of furanosides. O-Glycosidic epoxy alcohols gave only one, easily purified, aldehyde in approximately 30-60% yield depending on the substitution pattern. READ MORE
-
3. Asymmetric Formation and Isomerization of Three-Membered Rings : Catalyst Development and Evaluation
Abstract : Enantiopure α-amino acid derivatives were prepared using a protocol which allows for highly controlled regio- and chemoselectivity in the hydrogenation/ hydrogenolysis of aza-Diels-Alder adducts. One of the resulting α-amino esters, (1S,3R,4R)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid ethyl ester, was utilized further as a catalyst precursor. READ MORE
-
4. Allylic alcohols and aziridines from alkenes : Studies in asymmetric catalysis
Abstract : The development of methodology for asymmetric catalytic transformation of alkenederivatives is summarized. The studies concern the [a] Cu(I)-catalyzed allylic oxidation,[b] isomerization of epoxides to allyl alcohols, and [c] Cu(I)-catalyzed alkeneaziridination, respectively.[a] The preparation of exo-2-azabicyclo[2.2. READ MORE
-
5. New synthetic routes to azaspiro alkaloids : Applications to the synthesis perhydrohistrionicotoxin
Abstract : Perhydrohistrionicotoxin, 1, is related to a family of alkaloids which display pharmacologically interesting properties. The thesis deals with development of new methods for the chemical synthesis of such alkaloids, and is divided into three parts according to the different approaches. READ MORE