Search for dissertations about: "epoxides"

Showing result 1 - 5 of 38 swedish dissertations containing the word epoxides.

  1. 1. Cob(I)alamin as a Quantitative Tool for Analysis, Metabolism and Toxicological Studies of Electrophilic Compounds : Butadiene Epoxides, Glycidamide and Sucralose

    University dissertation from Stockholm : Department of Materials and Environmental Chemistry, Stockholm University

    Author : Hitesh Vijay Motwani; Stockholms universitet.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Environmental chemistry; NATURVETENSKAP Kemi Miljökemi; miljökemi; Environmental Chemistry;

    Abstract : Vitamin B12 can be reduced to cob(I)alamin [Cbl(I)], which is one of the most powerful nucleophiles known and referred to as a “supernucleophile”. Cbl(I) was applied as a tool in toxicological studies of the air pollutant 1,3-butadiene (BD), the toxicant acrylamide (AA) present in many foods, and the artificial sweetener sucralose. READ MORE

  2. 2. Biochemical Studies on a Plant Epoxide Hydrolase Discovery of a Proton Entry and Exit Pathway and the Use of In vitro Evolution to Shift Enantioselectivity

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ann Gurell; Uppsala universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; epoxide hydrolase; enantioselectivity; in vitro evolution; proton wire; epoxides; selectivity; CASTing; structure-function; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Biokemi; Biochemistry;

    Abstract : The work leading to this thesis has provided additional information and novel knowledge concerning structure-function relationship in the potato epoxide hydrolase.Epoxide hydrolases are enzymes catalyzing the hydrolysis of epoxides to yield the corresponding vicinal diols. READ MORE

  3. 3. Chemo-Enzymatic Epoxidation of Unsaturated Fatty Acids

    University dissertation from Biotechnology, Lund University

    Author : Cecilia Orellana Coca Åkerman; Lund University.; Lunds universitet.; [2006]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bioteknik; Biotechnology; solvent-free process.; Candida antarctica lipase B esterification; chemo-enzymatic epoxidation; Unsaturated fatty acids; epoxides;

    Abstract : Epoxy fatty acids are useful molecules and find a number of applications e.g. as PVC plasticisers and stabilisers, additives in polyurethane production, reactive diluents in paints, corrosion protection agents, etc. READ MORE

  4. 4. Stereoselective Nucleophilic Additions to α-Amino Aldehydes: Application to Natural Product Synthesis

    University dissertation from Stockholm : KTH

    Author : Per Restorp; KTH.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Stereoselective synthesis; Substrate-control; α-Amino aldehydes; Mukaiyama aldol; Allylsilanes; [3 2]-Annulation; -Alexine; DGDP; Vinyl epoxides; Regioselectivity; Alkyne nucleophiles; NATURAL SCIENCES Chemistry Organic chemistry; NATURVETENSKAP Kemi Organisk kemi;

    Abstract : This thesis deals with the development and application of new synthetic methodology for stereo- or regioselective construction of carbon-carbon bonds in organic synthesis.The first part of this thesis describes the development of a divergent protocol for stereoselective synthesis of chiral aminodiols by employing Mukaiyama aldol additions to syn- and anti-α-amino-β-silyloxy aldehydes. READ MORE

  5. 5. Quantitative analysis of DNA adducts formed by some epoxides of industrial importance

    University dissertation from Stockholm : Karolinska Institutet, Biosciences and Nutrition

    Author : Kamila Plná; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA adducts; 32P-postlabelling; cancer; genotoxicity; occupational; epoxides; allyl glycidyl ether; propylene oxide; epichlorohydrin;

    Abstract : The work presented herein has focused on DNA adduct formation by three industrial epoxides, allyl glycidyl ether, propylene oxide and epichlorohydrin. Epoxides, owing to the strained oxirane ring are chemically reactive and can alkylate various sites in DNA. READ MORE