Search for dissertations about: "erythropoiesis"

Showing result 1 - 5 of 35 swedish dissertations containing the word erythropoiesis.

  2. 1. Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation

    Author : Johan Flygare; Stefan Karlsson; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; RNA interference; Erythropoiesis; Lentiviral vectors; Nucleolus; Diamond-Blackfan anemia; Gene therapy; extracellulära vätskor;

    Abstract : Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents as macrocytic anemia during infancy. Linkage analysis suggests that at least four genes are associated with DBA of which two have been identified so far. READ MORE

  4. 2. Erythropoiesis in anemia of rencl failure and malignancy : Studies on erythropoietin, iron, and transferrin receptor : by Soheir Beshara

    Author : Soheir Beshara; Uppsala universitet; []
    Keywords : Medical sciences; erythropoiesis; anemia; renal transplantation; prostatic adenocarcinoma; erythropoietin; transferrin receptor; hemorheology positron emission tomography; iron hydroxide sucrose; pharmacokinetics; iron deficiency; 52Fe; 59Fe; red cell utilization; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Internal Medicine; invärtesmedicin;

    Abstract : Erythropoietin (Epo) and iron are essential requirements for erythropoiesis. Serum transferrin receptor (S-TfR) is a marker of total erythropoiesis and tissue iron availability. In patients with renal insufficiency, successful renal transplantation leads to correction of anemia and improvement in erythropoiesis. READ MORE

  5. 3. Studies of the Ribosomal Protein S19 in Erythropoiesis

    Author : Hans Matsson; Niklas Dahl; Leif Carlsson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; RPS19; Rps19; erythropoiesis; erythroblastopenia; Diamond-Blackfan; anemia; Genetik; Genetics; Genetik;

    Abstract : Ribosomal proteins are components of the ribosome, the protein synthesis machinery. The ribosomal protein S19 gene (RPS19) is mutated in Diamond-Blackfan anemia, DBA, which is a rare congenital anemia with absence or reduction of erythroid precursors in bone marrow. In this thesis, the role of RPS19 in erythropoiesis is investigated. READ MORE

  6. 4. Erythropoiesis and calcium homeostasis : a clinical study in uremia and kidney transplantation

    Author : Janusz Goch; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  7. 5. Diamond-Blackfan anemia : Mapping and identification of the disease gene

    Author : Peter Gustavsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Diamond-Blackfan anemia; erythropoiesis; positional cloning; chromosome 19q13; ribosomal protein S19 gene; Genetik; Clinical genetics; Klinisk genetik; Clinical Genetics; klinisk genetik;

    Abstract : This thesis presents the positional cloning of the gene behind Diamond-Blackfan anemia. Evidence for the involvement of ribosomal protein (RP) S19 gene mutations in Diamond-Blackfan anemia is given. This is the first example of a human disease that is directly related to a ribosomal protein. READ MORE