Search for dissertations about: "erythropoiesis"
Showing result 16 - 20 of 35 swedish dissertations containing the word erythropoiesis.
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16. Studies on treatment of renal anemia in patients on chronic hemodialysis
Abstract : In patients with chronic kidney disease, treatment with erythropoiesis-stimulating agents (ESA) effectively corrects anemia. Most of these patients also need supplementation with regular iron injections to secure iron availability for proper erythropoiesis. READ MORE
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17. Genotype-phenotype relations in SF3B1 mutated myelodysplastic syndromes with ring sideroblasts
Abstract : Myelodysplastic syndrome with ring sideroblasts (MDS-RS) is a clonal hematopoietic stem cell disorder characterized by hyperplastic and ineffective erythropoiesis, ring sideroblasts in the bone marrow, and anemia. Heterozygous mutations in the spliceosome gene SF3B1 are found in a majority of MDS-RS cases and are associated with the ring sideroblast phenotype and a favorable prognosis. READ MORE
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18. Cardiovascular and hematological responses to voluntary apnea in humans
Abstract : This thesis deals with cardiovascular and hematological responses to voluntary apnea in humans, with a special focus on O2 usage and storage. Humans, and many other air‐breathing animals, respond to apnea (breath holding) with a collection of interacting cardiovascular reflexes, which are collectively called the diving response. READ MORE
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19. Transcriptional regulation and effects on differentiation by LMO proteins and the basic helix-loop-helix factors TAL1 and HEN1
Abstract : Acute lymphoblastic leukemia (ALL) is the most widespread type of cancer, as well as the most frequent leukemia in children. Malignant ALL cells originate from normal T lymphocytes or B cells that are blocked at immature stages of differentiation. READ MORE
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20. Mitochondrial Iron Metabolism : Study of mitoferrin in Drosophila melanogaster
Abstract : Iron has a dualistic character. On the one hand it is essential for the life of most organisms, on the other hand it is involved in the generation of reactive oxygen species that are implicated in diseases and aging. READ MORE