Search for dissertations about: "establishment new cell line"
Showing result 1 - 5 of 9 swedish dissertations containing the words establishment new cell line.
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1. Predictive Markers of Treatment Resistance in Head and Neck Squamous Cell Carcinoma
Abstract : Head and neck cancer is a common malignancy with approximately 600 000 new cases yearly. Disappointingly, the overall survival has not increased over the last decades. The concept of personalized medicine, i.e. READ MORE
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2. Therapeutic potential of natural killer cells in multiple myeloma
Abstract : Multiple Myeloma (MM) is an incurable plasma cell neoplasm with a median length of survival after diagnosis of approximately three years; therefore new treatment modalities to eradicate the disease are needed. Although the disease remains incurable, current main alternatives are drug treatment modalities and autologous stem cell transplantation (ASCT). READ MORE
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3. Transposable Elements in Neural Progenitor Cells
Abstract : More than 90% of DNA does not code for proteins and for a long time these sequences were referred to as “junk DNA” due to their unknown purpose. With the advent of new technologies it is now known, that the non-coding part of the genome is of great importance for regulating gene expression and is therefore indispensable. READ MORE
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4. Host organelles and transporters in underground plant-pathogen interactions
Abstract : This thesis covers studies of three different soilborne plant pathogens, the two fungi, Rhizoctonia solani and Verticillium longisporum, and the protist Plasmodiophora brassicae, as well as their host responses. Based on genome sequence analysis of the pathogens and their plant hosts, different effectors and plant defence factors were predicted. READ MORE
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5. Preclinical Development of Imaging Agents for HER2 Expression in Prostate Cancer Using Radiolabeled Affibody Molecules
Abstract : This thesis is focused on pre-clinical evaluation of in vivo detection of HER2-expression in prostate cancer (PCa) patients and on the possibility of using targeted molecular imaging to personalize treatment of disseminated PCa. The work is divided into three distinct parts: (1) the establishment of a preclinical model for further studies, (2) imaging of HER2 in a murine model of PCa and (3) exploration of new treatment regimes against PCa. READ MORE