Search for dissertations about: "evolution membrane proteins"

Showing result 1 - 5 of 62 swedish dissertations containing the words evolution membrane proteins.

  2. 1. Membrane-bound proteins : Characterization, evolution, and functional analysis

    Author : Misty M. Attwood; Helgi B. Schiöth; Arne Elofsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transmembrane protein; alpha-helical membrane protein; evolution membrane proteins; 3TM; 4TM; 5TM; trispanin; Bioinformatics; Bioinformatik;

    Abstract : Alpha-helical transmembrane proteins are important components of many essential cell processes including signal transduction, transport of molecules across membranes, protein and membrane trafficking, and structural and adhesion activities, amongst others. Their involvement in critical networks makes them the focus of interest in investigating disease pathways, as candidate drug targets, and in evolutionary analyses to identify homologous protein families and possible functional activities. READ MORE

  4. 2. The Membrane Proteome : Evolution, Characteristics and Classification

    Author : Markus Sällman Almén; Helgi Schiöth; Robert Fredriksson; Marc Robinson-Rechavi; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Membrane proteome; molecular evolution; GPCRs; Dispanins; IFITM; Medicinsk vetenskap; Medical Science;

    Abstract : Membrane proteins are found in all kingdoms of life and are essential for cellular interactions with the environment. Although a large research effort have been put into this group many membrane proteins remains uncharacterized, both in terms of function and evolutionary history. READ MORE

  5. 3. Identification, Characterization and Evolution of Membrane-bound Proteins

    Author : Pär J. Höglund; Helgi B. Schiöth; Robert Fredriksson; Gert Vriend; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; G protein-coupled receptor; GPCR; Solute Carriers; SLC; Bioinformatics; Evolution; Rhodopsin; Adhesion; Phylogeny; Pharmacology; Farmakologi;

    Abstract : Membrane proteins constitute approximately 30% of all genes in the human genome and two large families of membrane proteins are G protein-coupled receptors (GPCRs) and Solute Carriers (SLCs) with about 800 and 380 human genes, respectively.In Papers I, II and IV, we report 16 novel human Adhesion GPCRs found by searches in NCBI and Celera databases. READ MORE

  6. 4. Dual-topology membrane proteins in Escherichia coli

    Author : Susanna Seppälä; Gunnar von Heijne; Dirk Jan Slotboom; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein topology; dual-topology; evolution; Escherichia coli; Biochemistry; biokemi;

    Abstract : Cellular life, as we know it, is absolutely dependent on biological membranes; remarkable superstructures made of lipids and proteins. For example, all living cells are surrounded by at least one membrane that protects the cell and holds it together. READ MORE

  7. 5. From protein production to genome evolution in Escherichia coli

    Author : Susan Schlegel; Jan-Willem de Gier; Peter Neubauer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; BL21 DE3 ; protein production; membrane proteins; secretory proteins; genome evolution; Biochemistry; biokemi;

    Abstract : The aim of my Ph.D. studies was to improve production yields of membrane- and secretory proteins in the widely used E. coli protein production strain BL21(DE3). READ MORE