Search for dissertations about: "evolution"

Showing result 26 - 30 of 3048 swedish dissertations containing the word evolution.

  2. 26. Evolutionary trajectories of Klebsiella pneumoniae : From experimental biofilm evolution to a hospital outbreak

    Author : Greta Zaborskytė; Linus Sandegren; Vaughn S. Cooper; Uppsala universitet; []
    Keywords : Klebsiella pneumoniae; evolution; experimental evolution; biofilms; infection; bacterial pathogens; Mikrobiologi; Microbiology;

    Abstract : Bacterial evolution is closely intertwined with our lives. As their hosts, we shape how bacteria evolve by imposing numerous selective pressures during the time bacteria spend in our bodies. As a result, they adapt in various ways to colonize us or infect us better. READ MORE

  4. 27. Evolution and host-specific adaptations of Legionella pneumophila

    Author : Anaísa B. Moreno; Lionel Guy; Dan I. Andersson; Fredrik Söderbom; Alexander W. Ensminger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Evolution; Legionella pneumophila; host-adaptation; experimental evolution; Acanthamoeba castellanii; transfection; Mikrobiologi; Microbiology;

    Abstract : How bacteria evolve pathogenic traits is shaped by their communities and environments. Legionella pneumophila is ubiquitous in aquatic habitats, where it persists by replicating within a broad range of protozoan hosts. Using the same mechanisms, L. READ MORE

  5. 28. Genome Evolution and Host Adaptation in Bartonella

    Author : Eva Caroline Berglund; Siv GE Andersson; Brendan Wren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bartonella; genome evolution; genome diversity; phage; gene transfer agent; secretion system; microarray; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Abstract : Bacteria of the genus Bartonella infect the red blood cells of a wide range of wild and domestic mammals and are transmitted between hosts by blood-sucking insects. Although most Bartonella infections are asymptomatic, the genus contains several human pathogens. READ MORE

  6. 29. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution

    Author : Oxana Lundström; Arne Elofsson; Liberles-Siltberg Jessica; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; intrinsically disordered proteins IDPs ; tandem repeats; short tandem repeats STRs ; genetic variation; orphan proteins; GC content; human STR variation; colorectal cancer; gene expression; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Abstract : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. READ MORE

  7. 30. Protein Folding, Binding and Evolution : PDZ domains and paralemmins as model systems

    Author : Greta Hultqvist; Per Jemth; Ruth Nussinov; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein folding; evolution; binding; allostery; Paralemmin; PDZ domain;

    Abstract : Proteins present at the synapse need to be multitasking in order to perform all vital functions in this limited space. In this thesis I have analyzed the function and evolution of such proteins, focusing on the PDZ domain and the paralemmin family. The PDZ domains bind to a wide variety of interaction partners. READ MORE