Search for dissertations about: "ewing"

Showing result 1 - 5 of 18 swedish dissertations containing the word ewing.

  1. 1. The role of epigenetics in multiple sclerosis development, progression and treatment

    Author : Ewoud Ewing; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis was to determine epigenetic changes in peripheral immune cells from Multiple Sclerosis (MS) patients. MS is a chronic inflammatory neurodegenerative disease, which initially presents itself during young adulthood. READ MORE

  2. 2. A novel technology for studying the disposition of drugs and toxicants in the lung : short inhalation exposures of the isolated and perfused rat lung to respirable dry particle aerosols

    Author : Pär Ewing; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Aerosol; inhalation; rat; lung; absorption; drugs; carcinogen; particles;

    Abstract : The disposition of solutes following the deposition of inhaled substances in the lung is a complex process that proceeds along parallel paths; passive diffusion of solutes through the air/blood barrier and local metabolism followed by blood-borne clearance to the circulation. Using the isolated and perfused lung (IPL) the pulmonary disposition of inhaled particles can be studied in great detail without interference from distal organs and systemic exposure. READ MORE

  3. 3. Exploring the Boundaries of Patent Commercialization Models via Litigation

    Author : Thomas Ewing; Chalmers tekniska högskola; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; theory of the firm; Intellectual property rights; licensing; patents; governance; innovation economics; research and development; technology management; value appropriation; strategy;

    Abstract : This thesis explores direct patent commercialization via patent assertion, particularly patent infringement litigation, a complex nonmarket activity whose successful undertaking requires knowledge, creativity, and financial resources, as well as a colorable infringement case. Despite these complexities, firms have increasingly employed patents as competitive tools via patent assertions, particularly in the United States. READ MORE

  4. 4. Indirect Exploitation of Intellectual Property Rights By Corporations and Investors: IP Privateering & Modern Letters of Marque & Reprisal

    Author : Thomas Ewing; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; equity; non-practicing entity NPE ; innovation system; unclean hands; indirect exploitation; Intellectual property IP ; patent troll; patent misuse; privateer; intellectual property right IPR ; patent; operating company; tortious interference; corporate formalism; antitrust; investor; competition;

    Abstract : Competitive pressures and rent-seeking behaviors have motivated companies and investors to develop indirect techniques for beneficially exploiting third-party intellectual property rights (IPRs) that qualitatively depart from the slate of direct exploitation tools whose usage has been honed during the past 30 years of the pro-patent era. Companies have increasingly realized that they do not need to create IPRs themselves to exploit them beneficially, which has been the conventional usage pattern. READ MORE

  5. 5. Micellar electrokinetic chromatography with laser-induced fluorescence detection applied to the analysis of biological samples

    Author : Gunnar Thorsén; Andrew G Ewing; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical Chemistry; analytisk kemi;

    Abstract : The research presented in this thesis is focused on the potential for using the combination of micellar electrokinetic chromatography with laser-induced fluorescence detection for the determination of compounds in biological samples. The topics that have been addressed are the development of separation electrolytes, the need for sample preparation procedures, the derivatization of the compounds of interest and the detection of these by laser-induced fluorescence. READ MORE