Search for dissertations about: "exhaled NO"

Showing result 21 - 25 of 55 swedish dissertations containing the words exhaled NO.

  1. 21. Charting the human lung with inhaled nanoparticles : Development of AiDA - a new diagnostic technique for respiratory disease

    Author : Jonas Jakobsson; NanoLund: Centre for Nanoscience; []
    Keywords : Aerosol; lung; lung deposition; respiratory tract; nanoparticles; ultrafine particles; airspace dimension assessment; AiDA; Chronic obstructive pulmonary disease; COPD; lung morphology;

    Abstract : Changes to the smallest structures of the distal lung are often the first sign of severe respiratory disease, but to date methods to detect and quantify these changes are limited. Chronic obstructive pulmonary disease (COPD) is currently estimated to be the third most common cause of death worldwide, but is to a large extent under-diagnosed, especially at early stages. READ MORE

  2. 22. Hypoxic pulmonary vasoconstriction and nitric oxide

    Author : Kristina Hambraeus Jonzon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : hypoxia; pulmonary vasoconstriction; regional pulmonary bloodflow; stimulus-response; nitric oxide; blood-borne distant effects; nitric oxide synthase activity; inhaled; exhaled; non-enzymatic;

    Abstract : Hypoxia causes pulmonary vasoconstriction (HPV), improving oxygenation by redistribution of the pulmonary blood flow to better oxygenated lung regions. HPV is intrinsic to the pulmonary vascular smooth muscle cell, but can be modulated by several vasoactive substances, as for example endothelium derived nitric oxide (NO) and endothelin-1 (ET-1). READ MORE

  3. 23. Non-invasive analysis of leukotrienes as biomarkers of airway inflammation : method development and clinical applications

    Author : Flora Gaber; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Airway inflammation; aspirin-intolerant asthma; biomarker; exhaled breath condensate; FENO; induced sputum; leukotrienes; 5-lipoxygenase; non-invasive analysis; saliva;

    Abstract : Asthma and chronic obstructive pulmonary disease (COPD) are two common diseases characterized by chronic airway inflammation, but the inflammation in asthma is different from the one in COPD. In addition, asthma is a heterogeneous disease presenting with many different phenotypes (e.g. READ MORE

  4. 24. Nitric oxide in experimental pulmonary embolism

    Author : Kristofer F Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nitric oxide (NO) is an important modulator of the pulmonary circulation both at basal state and in pulmonary hypertension. Low levels of NO are detectable in exhaled gas which is believed to mirror pulmonary NO formation and elimination. READ MORE

  5. 25. The Role of Nitric Oxide in Host Defence Against Mycobacterium tuberculosis : Clinical and Experimental Studies

    Author : Jonna Idh; Thomas Schön; Olle Stendahl; Åse Bengård Andersen; Linköpings universitet; []
    Keywords : ;

    Abstract : Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), responsible for significant morbidity and mortality worldwide, especially in low-income countries. Considering aggravating factors, such as HIV co-infection and emerging drug resistance, new therapeutic interventions are urgently needed. Following exposure to M. READ MORE