Search for dissertations about: "exocrine pancreatic insufficiency"

Found 5 swedish dissertations containing the words exocrine pancreatic insufficiency.

  1. 1. CCK-dependent pancreatic regulation and pancreatic functional impact on growth in young pigs

    Author : Sofia Rengman; Lunds universitet.; Lund University.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; pancreatin; pig; exocrine pancreatic insufficiency; pancreatic duct ligation; insulin; entero-pancreatic reflex; CCK-receptors; pentagastrin; Exocrine pancreas; cholecystokinin;

    Abstract : The exocrine pancreas is mainly regulated via neuro-hormonal pathways. CCK-dependent regulatory pathways and CCK-receptor subtype involved seem to differ between mammalian species. READ MORE

  2. 2. The role of exocrine pancreas for feed intake and growth. Studies in a model with exocrine pancreatic insufficient young pigs

    University dissertation from Department of Cell and Organism Biology, Lund University

    Author : Olexandr Fedkiv; Lunds universitet.; Lund University.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; exocrine pancreatic insufficiency; pigs; pancreatic duct ligation; adaptation;

    Abstract : Popular Abstract in Swedish Bukspottkörteln (pankreas) består av en sekretorisk (exokrin) del, som producerar pankreassaft innehållande olika matspjälkningsenzymer vilka medverkar vid nedbrytningen av födan i tarmen, samt en hormoninsöndrande (endokrin) del, som producerar insulin och andra hormon vilka reglerar näringsomsättningen i kroppen. Vid en underproduktion av enzymer, exokrin pankreatisk insufficiens (EPI), som kan uppstå vid sjukdom, såsom cystisk fibros och kronisk pankreasinflammation, eller efter kirurgiska ingrepp, såsom pankreatotomi och ligering av pankreas utförsgång, uppstår olika problem i mag-tarmkanalen som leder till försämrad matsmältning och näringsupptag och slutligen undernäring. READ MORE

  3. 3. LXR and aromatase knock-out mice : Animal models providing insight into human diseases

    University dissertation from Stockholm : Karolinska Institutet, Biosciences and Nutrition

    Author : Hyun-Jin Kim; Karolinska Institutet.; Karolinska Institutet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In our characterization of mouse strains carrying mutations in nuclear receptor and aromatase genes we have found phenotypes which resemble four human diseases: benign prostatic hyperplasia (BPH), Sjögren s syndrome (SS), amyotrophic lateral sclerosis (ALS), and exocrine pancreatic insufficiency. The work in this thesis was designed to understand the roles of LXRalpha, LXRbeta and aromatase in development of these diseases and to investigate whether these animal models help us (1) to understand the etiology of the corresponding human diseases and (2) to develop new therapeutic approaches for the treatment of these diseases. READ MORE

  4. 4. Studies on the phenotype of LXRbeta-/- mice : From malabsorption to amyotrophic lateral sclerosis

    University dissertation from Stockholm : Karolinska Institutet, Biosciences and Nutrition

    Author : Chiara Gabbi; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors belonging to the superfamily of ligand-activated transcription factors with a key role in the control of lipid and glucose metabolism. Studies of the phenotype of LXRalpha-/- mice and LXRbeta-/- mice have shown that these nuclear receptors have specific and distinct roles, although they share very high sequence homology (78%). READ MORE

  5. 5. Gastroduodenal epithelial transport in patients with cystic fibrosis

    University dissertation from Göteborg

    Author : Karin Edshage Hallberg; Göteborgs universitet.; Gothenburg University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystic fibrosis; CFTR; intestinal motility; gastric secretion; IgA; Ussing chamber; intestinal permeability; genotype;

    Abstract : Cystic fibrosis (CF) is an inherited disease where respiratory failure due to chronic lung infection is the major cause of death. A defective protein, cystic fibrosis transmembrane conductance regulator (CFTR) alters chloride epithelial transport. READ MORE