Search for dissertations about: "exosomes"

Showing result 1 - 5 of 47 swedish dissertations containing the word exosomes.

  1. 1. Immunomodulation during human pregnancy placental exosomes as vehicles of immune suppression

    University dissertation from Umeå : Umeå Universitet

    Author : Ann-Christin Stenqvist; Umeå universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; exosomes; microvesicles; pregnancy; placenta; syncytiotrophoblast; immune privilege; apoptosis; cytotoxicity; T regulatory cells; NKG2D; MICA B; FasL; TRAIL; immunologi; Immunology;

    Abstract : The mammalian pregnancy comprises a challenge to the maternal immune system since the fetus is semi-allogeneic and could thus be rejected. Pregnancy success is associated with the placenta that is not only essential for oxygen supply, nourishment and pregnancy hormones but also plays a role in the protection of the fetus against maternal immunologic attack. READ MORE

  2. 2. Immune modulation in serous epithelial ovarian cancer focus on the role of tumor-derived exosomes

    University dissertation from Umeå : Umea University

    Author : Alireza Labani Motlagh; Umeå universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

    Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE

  3. 3. Exosomes - characterisation of the RNA and protein cargo

    University dissertation from Göteborg : University of Gothenburg

    Author : Cecilia Lässer; Göteborgs universitet.; Gothenburg University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astma; body fluid; breast milk; chronic rhinosinusitis; exosomes; extracellular vesicles; nasal lavage; plasma; proteomics; RNA; saliva;

    Abstract : .... READ MORE

  4. 4. Physical characterization of exosomes and other extracellular vesicles using surface-based sensing

    University dissertation from Göteborg : University of Gothenburg

    Author : Deborah Rupert; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nanoparticle tracking analysis; exosomes; scattering; surface-based biosensing; optical density; cluster of differentiation 63 CD63 ; liposomes; label-free; fluorescence; surface plasmon resonance; Extracellular vesicles; specificity; antibody; lipid content; single particle; quantification; size distribution; optical waveguide microscopy;

    Abstract : Extracellular vesicles (EVs) are hundred of nanometer sized particles secreted by almost all cell types. Exosomes are one type of EVs today intensively investigated due to the increased evidence suggesting that they play important roles as communicating vehicles in a broad range of physiological processes, pathological conditions and disease diagnostics. READ MORE

  5. 5. The role of exosomes and microflora in establishing mucosal tolerance and the protection against allergic disease

    University dissertation from Göteborg : University of Gothenburg

    Author : Nina Almqvist; Göteborgs universitet.; Gothenburg University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oral tolerance; exosomes; allergy;

    Abstract : The role of exosomes and microflora in establishing mucosal tolerance and the protection against allergic disease Nina Almqvist, Departement of Rheumatology and Inflammation Research, The Sahlgrenska Academy University of Gothenburg, Guldhedsgatan 10A, 413 46 Göteborg, Sweden The breakdown of immune regulation to innocuous environmental antigens at mucosal sites can result in a number of different diseases such as, allergies and inflammatory bowel disease (IBD). Allergy is one of the most common diseases with a prevalence of up to 40% in children from developed countries. READ MORE