Search for dissertations about: "exosomes"

Showing result 21 - 25 of 50 swedish dissertations containing the word exosomes.

  1. 21. Some Characteristics of Human Prostasomes and Their Relationship to Prostate Cancer

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Göran Ronquist; Uppsala universitet.; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostasomes; prostate; prostate cancer; clusterin; antibodies; metastasis; exosomes; PC-3 cells; DNA vehicles; gene therapy; immunoblotting; mass spectrometry; agarose gel electrophoresis; vertebral metastasis.; MEDICINE Chemistry Clinical chemistry; MEDICIN Kemi Klinisk kemi; Clinical Chemistry; klinisk kemi;

    Abstract : Background: The secretory epithelial cells of the prostate gland use sophisticated vehicles named prostasomes to relay important information to sperm cells in semen. This prostasome-forming and secretory ability of the epithelial cells is also preserved in poorly differentiated prostate cancer cells. READ MORE

  2. 22. Mechanistic Studies On the Role of Polyamines and Microvesicles in Tumor Growth and Hypoxia-mediated Angiogenesis

    University dissertation from Lund University, Faculty of Medicine

    Author : Katrin Svensson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; angiogenesis; hypoxia; microvesicles; exosomes; polyamines; tissue factor; coagulation;

    Abstract : Solid tumors are composed of cancer cells, as well as resident or infiltrating non-malignant cells that contribute to the malignant state in an ecosystem generally accepted as the tumor microenvironment. Microenvironmental tumor hypoxia is the foremost leading cause of angiogenesis, i.e. READ MORE

  3. 23. Exosomes : Nano-vesicles in immune regulation

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Sara M Johansson; Karolinska Institutet.; Karolinska Institutet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Nano-vesicles (30-100 nm) with an endosome-derived limiting membrane are called exosomes. These are released from the cell when the endosome fuses with the outer cell membrane. Exosomes from antigen presenting cells (APC) carry MHC class I and class II as well as integrins, tetraspanins and co-stimulatory molecules. READ MORE

  4. 24. Exosomes : immunomodulators in cancer and therapy

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Stefanie Hiltbrunner; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Exosomes are nano-sized membrane vesicles derived from the late endosomal compartment. They are capable of transferring proteins, lipids and RNA between cells. B cell and dendritic cell (DC)-derived exosomes express major histocompatibility complex (MHC) class I and II, as well as costimulatory molecules (CD80/86) and can initiate T cell responses. READ MORE

  5. 25. Exosomes in immune regulation and allergy

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Charlotte Admyre; Karolinska Institutet.; Karolinska Institutet.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Exosomes are nano-sized vesicles of endosomal origin which are secreted from several different cell types. Depending on their cellular source they have been suggested to have different functions, like having a role in antigen delivery and T cell activation (antigen presenting cell-derived exosomes) or a role in tolerance induction (epithelial cell-derived exosomes). READ MORE