Search for dissertations about: "exosomes"

Showing result 36 - 40 of 63 swedish dissertations containing the word exosomes.

  2. 36. Oral mucosa keratinocytes and their exosomes for epithelial tissue regeneration

    Author : Sebastian Sjöqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Early tumors, including high grade dysplasia and intramucosal invasive cancer, of the esophagus can today be removed using endoscopic resection, often using a technique called endoscopic submucosal dissection (ESD). This treatment is better tolerated and has considerably less mortality and morbidity compared to conventional, more invasive surgery, which usually entails esophagectomy. READ MORE

  4. 37. Exosomes and the NKG2D receptor-ligand system in pregnancy and cancer : using stress for survival

    Author : Malin Hedlund; Lucia Mincheva-Nilsson; Susanne Gabrielsson; Umeå universitet; []
    Keywords : Exsosomes; NKG2D; MICA; MICB; ULBP; human placenta; trophoblast; syncytiotrophoblast; thermal stress; oxidative stress; leukemia; lymphoma; immunologi; Immunology;

    Abstract : Although not obvious at first sight, several parallels can be drawn between pregnancy andcancer. Many proliferative, invasive and immune tolerance mechanisms that supportnormal pregnancy are also exploited by malignancies to establish a nutrient supply andevade or edit the immune response of the host. READ MORE

  5. 38. Studies on the molecular and functional properties of exosomes in the metastatic prostate cancer bone microenvironment

    Author : Ioulia Vardaki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prostate cancer is the most common cancer type and the second leading cancer related cause of death worldwide in men. Prostate cancer patients initially respond to standard treatment (e.g., hormonal, surgery/irradiation) but about 30% of them will develop resistance and progress to metastatic Castration Resistant Prostate Cancer (mCRPC). READ MORE

  6. 39. Advances in exosome-mediated immunotherapy and diagnostics

    Author : Pia Larssen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Exosomes are small vesicles with immune-stimulatory capacity, which can activate T cell responses in a B cell dependent manner, and therefore may serve as immune therapeutic tools. Peptide-loaded dendritic cell (DC)-derived exosomes are proven safe in clinical trials, although with limited ability to induce cytotoxic T lymphocyte (CTL) responses or prolong patient survival. READ MORE

  7. 40. Extracellular vesicles : mediators of immune modulation in the lung and as therapeutic vehicles

    Author : Casper Ullsten-Wahlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Extracellular vesicles (EVs) are released from all cell types, and carry a wide setup of proteins, nucleic acids, lipids and other cargo. The overall aim of this thesis is to explore EV-based immune therapy, but also to find clues on mechanisms of the inflammatory disease sarcoidosis, and of lung cancer. READ MORE