Search for dissertations about: "exosomes"

Showing result 41 - 45 of 63 swedish dissertations containing the word exosomes.

  2. 41. Analysis of extracellular vesicles and their application in immunotherapy

    Author : Rosanne E Veerman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Extracellular Vesicles (EVs) are nano-sized particles secreted by most, if not all, cell types. They are important mediators in intercellular communication and carry a broad array of biomolecules such as lipids, nucleic acids and proteins. READ MORE

  4. 42. Studies on the regulation of leukotriene biosynthesis in antigen presenting cells

    Author : Julia Esser; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Leukotrienes (LTs) are pro-inflammatory lipid mediators with important roles in host de- fense and inflammatory disease. Leukotriene B4 (LTB4) is a potent chemoattractant for neutrophils and contributes to bacterial killing, while the cysteinyl leukotrienes (LTC4, LTD4 and LTE4) elicit increased vascular permeability, bronchoconstriction, eosinophil trafficking and mucus secretion. READ MORE

  5. 43. Interactions of engineered and endogenous nanoparticles with cells in the immune system

    Author : Helen Vallhov; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Nanotechnology is a fast developing area, which refers to research and technology development at the nanometer scale, ranging from 0.1-100 nm. The properties of nanomaterials offer the ability to interact with complex biological functions, implying enormous opportunities for novel applications within medicine. READ MORE

  6. 44. Mechanisms of inflammatory signalling in chronic lung diseases : transcriptomics and metabolomics approaches

    Author : Bettina Levänen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoidosis, asthma and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases with many different clinical phenotypes. A central characteristic of all three diseases is the altered airway function due to inflammation. READ MORE

  7. 45. Novel roles of ErbB3 receptor tyrosine kinase in vesicular trafficking

    Author : Ana Rosa Saez-Ibañez; Ingvar Ferby; Carl-Henrik Heldin; Johanna Ivaska; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ErbB3; Integrin; GGA3; Rabaptin5; PKD; Ack1; endocytic recycling; exosome; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : ErbB3 is a catalytically impaired receptor tyrosine kinase (RTK) from the EGFR family. Upon ligand binding, ErbB3 forms heterodimers with other members of the family and triggers phosphorylation cascades that promote crucial cellular functions as proliferation, differentiation and survival. READ MORE