Search for dissertations about: "experimental HIV-1 model"
Showing result 1 - 5 of 8 swedish dissertations containing the words experimental HIV-1 model.
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1. Enhancement of HIV-1 DNA immunogens
Abstract : Human immunodeficiency virus type 1 eludes control by the immune response through a high degree of variability and immune escape mechanisms. Induction of a broad specific immune response is important to clear virus-infected cells. READ MORE
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2. From Physicochemical Features to Interdependency Networks : A Monte Carlo Approach to Modeling HIV-1 Resistome and Post-translational Modifications
Abstract : The availability of new technologies supplied life scientists with large amounts of experimental data. The data sets are large not only in terms of the number of observations, but also in terms of the number of recorded features. READ MORE
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3. Studies on Potency and breadth of HIV-1, HIV-2 and SIV neutralizing antibody responses
Abstract : Even though the relative contribution of neutralizing antibodies (Nab) to prevent progression to AIDS during HIV-1 infection is still unclear, the induction of broadly NAb directed against HIV-1 through vaccination is considered to represent an important goal for the development of HIV-1 vaccines. Factors contributing to the induction of NAb may include the strength and duration of antigenic stimulation, the preservation of CD4+ T and B cells, the conformation of the HIV-1 envelope glycoprotein complex (Env), and the evolution of Env during infection. READ MORE
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4. Prime-boost immunization strategies against HIV-1
Abstract : Since the start of the global HIV epidemic in 1981, more than twentyfive million people have succumbed to AIDS-related diseases. The epidemic is most severe in Sub-Saharan Africa, where twentyfive million people are currently infected and more than two million died during 2006. READ MORE
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5. Exploring Ligand Binding in HIV-1 Protease and K+ Channels Using Computational Methods
Abstract : Understanding protein-ligand interactions is highly important in drug development. In the present work the objective is to comprehend the link between structure and function using molecular modelling. READ MORE