Search for dissertations about: "experimental animal model"

Showing result 1 - 5 of 310 swedish dissertations containing the words experimental animal model.

  1. 1. On optical methods for intracerebral measurements during stereotactic and functional neurosurgery : Experimental studies

    Author : Johan Antonsson; Karin Wårdell; Lars-Erik Augustinsson; Linköpings universitet; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Laser Doppler perfusion monitoring; Diffuse reflectance spectroscopy; Functional and stereotactic neurosurgery; Medical engineering; Medicinsk teknik;

    Abstract : Radio frequency (RF) lesioning and deep brain stimulation (DBS) are the two prevailing surgical treatments for movement disorders within the field of stereotactic and functional neurosurgery. For RF-lesioning, a small volume of brain tissue is coagulated and knowledge of the lesion size and growth is of great importance for the safety and outcome of the procedure. READ MORE

  2. 2. Topical anesthesia of the tympanic membrane : an experimental animal study

    Author : Sten-Hermann Schmidt; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Topical anesthesia; middle ear; tympanic membrane; cochlea; collagen fibres; lidocaine; 96 % phenol; Bonain s liquid; auditory brainstem response; ototoxicity; cytocochleogram; scanning electron microscopy; rat; guinea pig;

    Abstract : Myringotomy plays an important role in otological therapy. The procedure requires an efficient anesthesia, which can be obtained without general anesthesia. However, the use of local anesthetics on the tympanic membrane (TM) has been abandoned in many places, as general anesthesia has been readily available. READ MORE

  3. 3. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

    Author : Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Abstract : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. READ MORE

  4. 4. Experimental Helicobacter pylori infection in an animal model

    Author : Yi-Qian Sun; Torkel Wadström; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Background: Helicobacter pylori is a microaerophilic Gram-negative bacterium colonizing the human stomach. The prevalence of this infection is between 20-90% depending on geographic location. Comprehensive studies have shown significant relationships between H. pylori infection and chronic gastritis, peptic ulcer and gastric carcinoma. READ MORE

  5. 5. Experimental porcine models of retinal ischemia

    Author : Håkan Morén; Lund Oftalmologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; retinal ischemia; animal model; multifocal electroretinography; intraarterial coiling; retinal vasculature;

    Abstract : Retinal ischaemia resulting from e.g. diabetes, vein thrombosis or arterial occlusion, is one of the major causes of visual impairment and blindness. Although new methods of treatment are being developed, there is still a need for more effective pharmacological forms of treatment. READ MORE