Search for dissertations about: "experimental brain trauma"

Showing result 16 - 20 of 41 swedish dissertations containing the words experimental brain trauma.

2. 16. Genomic clues to secondary injury mechanisms in brain trauma

   Author : Christina von Gertten; Karolinska Institutet; Karolinska Institutet; []
   Keywords : traumatic brain injury; cerebral cortical contusion; weight-drop model; depolarisation; gene expression; nestin; MMP-9; TIMP-1; osteopontin; CD44; hippocalcin; NMDA receptor; microarray; rat;

   Abstract : Traumatic brain injury (TBI) is a heterogenous disease that can lead to persistent disability or death. The immediate mechanical disruption of brain tissue is followed by a phase of secondary brain injury. During this phase TBI challenges clinical interventions due to its complexity. READ MORE

4. 17. Nitric oxide in brain contusion

   Author : Caroline Gahm; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Apoptosis; Colchicine; Dexamethasone; eNOS; human; immunohistochemistry; iNOS; L-NAME; L-NIL; neuronal degeneration; Nimodipine; nitric oxide; NO; nNOS; rat; SPBN; Tirilazad Mesylate; traumatic brain injury;

   Abstract : Trauma to the brain is a leading cause of death and disability. The primary injury initiates a cascade of biochemical reactions in the brain that causes further neuronal damage, a process referred to as secondary brain injury. READ MORE

5. 18. Towards improved motorcycle helmet test methods for head impact protection : Using experimental and numerical methods

   Author : Shiyang Meng; Svein Kleiven; Peter Halldin; Mazdak Ghajari; KTH; []
   Keywords : Head Injuries; Helmet; Injury Prevention; Motorcycle; Test Standard; Finite Element Method; Applied Medical Technology; Tillämpad medicinsk teknik;

   Abstract : Head injury is the leading cause of death and major trauma for users of powered two-wheelers (PTWs). Helmet use can prevent and reduce head injuries when a crash is inevitable. However, today’s motorcycle helmets do not protect equally against all types of head injuries. READ MORE

6. 19. Modelling of Diffuse Brain Injury: Combining Methods to Study Possible Links between Transient Intracranial Pressure and Injury

   Author : Ulrika Krave; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; animal model; astrocytosis; diffuse axonal injury; neurofilaments; diffuse brain injury; rotational acceleration; closed head trauma; rabbit; finite element analysis; intracranial pressure; injury mechanisms;

   Abstract : The objectives of this research are the study of sagittal rotational acceleration induced diffuse brain injury mechanisms. Such injuries are common in vehicle accidents in particular; the consequences range from mild to severe symptoms and may lead to persistent neurological dysfunction. READ MORE

7. 20. Traumatic Brain Injuries: Animal Experiments and Numerical Simulations to Support the Development of a Brain Injury Criterion

   Author : Jacobo Antona; Chalmers tekniska högskola; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; traumatic brain injuries; traffic safety; concussions; animal experiments; finite element method;

   Abstract : Traumatic Brain Injuries (TBIs) account for about half of the 1 300 000 annual traffic related deaths and the 50 000 000 injuries worldwide. The burden of TBI is ethically unacceptable and economically unsustainable. READ MORE