Search for dissertations about: "exposure biomarker"
Showing result 1 - 5 of 112 swedish dissertations containing the words exposure biomarker.
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1. Proteomics in biomarker research : Insights into the effects of aging and environment on biological systems
Abstract : Proteomics is the global analysis of proteins that covers a broad range of technologies aimed at determining the identity and quantity of proteins expressed in the cell, their three-dimensional structure and interaction partners. In contrast to genome, proteome reflects more accurately on the dynamic state of the cell, tissue, or an organism. READ MORE
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2. Biomarkers of exposure to pesticides in humans
Abstract : Almost every human is exposed to pesticides, in work environments, by domestic use and via diet, drinking water and personal products. Current research expresses concern that low dose exposure over time can lead to adverse health effects. READ MORE
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3. Biomarkers of internal exposure/dose : Methods to quantify adducts to protein and DNA by LC/MS studied with benzo[a]pyrene and isocyanates
Abstract : This thesis focuses on methods for quantification by liquid chromatography/mass spectrometry (LC/MS) of specific biomarkers for internal dose of chemicals which induce toxicity through their electrophilic reactivity. In vivo such compounds are short-lived, and could feasibly be measured as their reaction products (adducts) with biomacromolecules. READ MORE
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4. Evaluation of Biomarker Responses in Fish : with Special Emphasis on Gill EROD Activity
Abstract : Many chemicals present in the aquatic environment can interfere with physiological functions in fish. Exposure to chemicals can be revealed by the use of biomarkers. Induction of 7-ethoxyresorufin O-deethylase (EROD) activity is a commonly used biomarker for exposure to CYP1A inducers such as dioxins and polyaromatic hyrdrocarbons. READ MORE
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5. Radiobiological effects of the thyroid gland - transcriptomic and proteomic responses to 131l and 211At exposure
Abstract : Radionuclides are widely used in medicine. 131I is one of the most employed radionuclides and is administered to patients either bound to tumor targeting molecules or as halide to target the thyroid or thyroid cancer. READ MORE