Search for dissertations about: "exposure in-vivo"

Showing result 1 - 5 of 351 swedish dissertations containing the words exposure in-vivo.

  1. 1. Studies of cadmium, mercury and lead in man. The value of X-ray fluorescence measurements in vivo

    University dissertation from Medical Radiation Physics, Lund University

    Author : Jimmy Börjesson; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physics; exposure assessment; smelter; half-time; fingerbone; occupational exposure; bone; thyroid; liver; kidney cortex; lead; mercury; cadmium; XRF; in vivo; Fysik; Chemistry; Kemi;

    Abstract : Two XRF methods have been used for in vivo studies of mercury, cadmium and lead. Persons with a history of long-term occupational mercury exposure had elevated mercury concentrations in their kidneys (up to 65 µg/g). The minimum detectable concentration varied between 12 and 45 µg/g. READ MORE

  2. 2. Engineered nanomaterials in in vivo and in vitro models

    University dissertation from Department of Physics, Lund University

    Author : Laura Abariute; [2018]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; III-V semiconductor nanowires; Nanoparticle exposure; Mouse exposure; Cell exposure; Nanotoxicology; Nanosafety; Fysicumarkivet A:2018:Abariute;

    Abstract : Nanotechnology and engineered nanomaterials (ENM) empower existing technologies. One of the great examples are III-V semiconductor nanowires (NW), which have a broad application range. The occupational safety and hazard organizations draw attention to ENM, as their physical and chemical characteristics differ from the ones of bulk materials. READ MORE

  3. 3. Improved basis for cancer risk assessment of acrylamide from food Determination of glycidamide in vivo doses

    University dissertation from Stockholm : Department of Materials and Environmental Chemistry (MMK), Stockholm University

    Author : Anna Vikström; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Environmental chemistry; NATURVETENSKAP Kemi Miljökemi; miljökemi; Environmental Chemistry;

    Abstract : Acrylamide is formed in heat processing of many common foods. According to animal cancer tests acrylamide is a carcinogen. To estimate the cancer risk from exposure via food, the response at high doses in the cancer tests with rats has to be extrapolated to the exposure levels in humans. READ MORE

  4. 4. β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity : Studies in vitro and in vivo

    University dissertation from Uppsala : Uppsala University

    Author : Lisa Ersson; Uppsala universitet.; [2020]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BMAA; neurotoxin; neurodegeneration; cellular transport; metabolic profiling; protein-association; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : β-N-methylamino-L-alanine (BMAA) is a neurotoxic non-proteinogenic amino acid produced naturally by cyanobacteria, diatoms and dinoflagellates and it has been detected in samples from fresh and marine water from all over the world. It can bioaccumulate in fish and shellfish, and has a potential to biomagnify in a terrestrial food chain. READ MORE

  5. 5. Development of Methods for Assessing Unbound Drug Exposure in the Brain In vivo, in vitro and in silico

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Fridén; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Drug transport; Tissue distribution; Transporters; Pharmacokinetics; PHARMACY Other pharmacy; FARMACI Övrig farmaci; PHARMACY Biopharmacy; FARMACI Biofarmaci; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The blood-brain barrier is formed by tightly joined capillary cells with transporter proteins and acts as to regulate the brain concentration of nutrients as well as many drugs. When developing central nervous system drugs it is necessary to measure the unbound drug concentration in the brain, i.e. the unbound brain exposure. READ MORE