Search for dissertations about: "exposure in-vivo"

Showing result 1 - 5 of 342 swedish dissertations containing the words exposure in-vivo.

  1. 1. Studies of cadmium, mercury and lead in man. The value of X-ray fluorescence measurements in vivo

    University dissertation from Medical Radiation Physics, Lund University

    Author : Jimmy Börjesson; [1996]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physics; exposure assessment; smelter; half-time; fingerbone; occupational exposure; bone; thyroid; liver; kidney cortex; lead; mercury; cadmium; XRF; in vivo; Fysik; Chemistry; Kemi;

    Abstract : Popular Abstract in Swedish Bestämning av koncentrationen av kadmium, kvicksilver och bly i människokroppen. Värdet av röntgenfluorescensmätningar in vivo... READ MORE

  2. 2. Engineered nanomaterials in in vivo and in vitro models

    University dissertation from Department of Physics, Lund University

    Author : Laura Abariute; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2018]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; III-V semiconductor nanowires; Nanoparticle exposure; Mouse exposure; Cell exposure; Nanotoxicology; Nanosafety; Fysicumarkivet A:2018:Abariute;

    Abstract : Nanotechnology and engineered nanomaterials (ENM) empower existing technologies. One of the great examples are III-V semiconductor nanowires (NW), which have a broad application range. The occupational safety and hazard organizations draw attention to ENM, as their physical and chemical characteristics differ from the ones of bulk materials. READ MORE

  3. 3. Improved basis for cancer risk assessment of acrylamide from food Determination of glycidamide in vivo doses

    University dissertation from Stockholm : Department of Materials and Environmental Chemistry (MMK), Stockholm University

    Author : Anna Vikström; Stockholms universitet.; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Chemistry Environmental chemistry; NATURVETENSKAP Kemi Miljökemi; miljökemi; Environmental Chemistry;

    Abstract : Acrylamide is formed in heat processing of many common foods. According to animal cancer tests acrylamide is a carcinogen. To estimate the cancer risk from exposure via food, the response at high doses in the cancer tests with rats has to be extrapolated to the exposure levels in humans. READ MORE

  4. 4. Development of Methods for Assessing Unbound Drug Exposure in the Brain In vivo, in vitro and in silico

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Fridén; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Blood-brain barrier; Drug transport; Tissue distribution; Transporters; Pharmacokinetics; PHARMACY Other pharmacy; FARMACI Övrig farmaci; PHARMACY Biopharmacy; FARMACI Biofarmaci; PHARMACY Pharmaceutical pharmacology; FARMACI Farmaceutisk farmakologi; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : The blood-brain barrier is formed by tightly joined capillary cells with transporter proteins and acts as to regulate the brain concentration of nutrients as well as many drugs. When developing central nervous system drugs it is necessary to measure the unbound drug concentration in the brain, i.e. the unbound brain exposure. READ MORE

  5. 5. The Hepatobiliary Transport of Rosuvastatin In Vivo

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ebba Bergman; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rosuvastatin; Biliary excretion; Transport inhibition; Pharmacokinetics; Drug-drug interactions; Hepatobiliary transport; Organic anion transporting polypeptide; OATP; Statins; Gemfibrozil; Cyclosporine; Imatinib; Rifampicin; Canalicular transport; Sinusoidal transport; Hepatic uptake; Hepatic extraction; PHARMACY Biopharmacy; FARMACI Biofarmaci; Biopharmaceutics; biofarmaci;

    Abstract : In vivo studies of hepatobiliary disposition are challenging. The hepatobiliary system is complex, as its physiological localization, complex cellular structure with numerous transporters and enzymes, and the interindividual variability in protein expression and biliary flow will all affect the in vivo disposition of a drug under investigation. READ MORE