Search for dissertations about: "expressed sequence tag"
Showing result 1 - 5 of 21 swedish dissertations containing the words expressed sequence tag.
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1. Sequencing of genes and genomes
Abstract : .... READ MORE
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2. Computational approaches for in-depth analysis of cDNA sequence tags
Abstract : Major recent improvements in biotechnology have led to an accelerated production of DNA sequences. The completion of the human genome sequence, along with the genomes of more than two hundred other species, has marked the arrival of the genome era. The ultimate goal is to understand the structure and function of genomes and their genes. READ MORE
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3. Molecular Phylogenetics of Mammals
Abstract : In this thesis, the phylogenetic relationships of the Mammalia have been studied at various levels. Different sources of genetic information have been evaluated and used as phylogenetic markers. These include the well-known mitochondrial genome, cDNA from housekeeping genes and expressed sequence tags from nuclear genes. READ MORE
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4. Mining the transcriptome - methods and applications
Abstract : Regulation of gene expression occupies a central role in the control of the flow of genetic information from genes to proteins. Regulatory events on multiple levels ensure that the majority of the genes are expressed under controlled circumstances to yield temporally controlled, cell and tissue-specific expression patterns. READ MORE
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5. Engineering of Affibody molecules for Radionuclide Molecular Imaging and Intracellular Targeting
Abstract : Affibody molecules are small (7 kDa) affinity proteins of non-immunoglobulin origin that have been generated to specifically interact with a large number of clinically important molecular targets.In this thesis, Affibody molecules have been employed as tracers for radionuclide molecular imaging of HER2- and IGF-1R-expressing tumors, paper I-IV, and for surface knock-down of EGFR, paper V. READ MORE