Search for dissertations about: "expression vector"

Showing result 1 - 5 of 120 swedish dissertations containing the words expression vector.

  1. 1. Adenovirus vector systems permitting regulated protein expression and their use for in vivo splicing studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Molin; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Adenovirus; vector; inducible; gene expression; ASF SF2; splicing; Biokemi; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; Medical Virology; medicinsk virologi;

    Abstract : We have constructed two adenovirus-based gene expression vector systems permitting regulated protein expression. They are based on the tetracycline-regulated Tet-ON- and the progesterone antagonist RU 486-regulated gene expression systems, which were rescued into E1-deficient adenovirus vectors. READ MORE

  2. 2. Replication-competent adenovirus 11p vector as a new oncolytic agent

    University dissertation from Umeå : Umeå universitet

    Author : Jim Silver; Umeå universitet.; Umeå universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virologi; Adenovirus; Vector; mikrobiologi; Microbiology;

    Abstract : Human adenoviruses (Ads) as vectors have been studied for cancer gene therapy for several decades due to their ability to shut down host cell replication and lyse tumour cells. Ad5 of species C is commonly used as a replication-defective or a replication-competent vector. READ MORE

  3. 3. Propionibacterium acnes and its phages

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Rolf Lood; Lunds universitet.; Lund University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Propionibacterium acnes; biofilm; bacteriophage; Siphovirus; pseudolysogeny; heme oxygenase; free radicals; recombinant protein expression; vector;

    Abstract : Popular Abstract in Swedish Mikroorganismer finns överallt! De klarar av att överleva i extrema miljöer, extrema pH, extrema temperaturer och kan motstå strålning och gift i doser som vi inte skulle överleva. Framförallt klarar mikroorganismer av att överleva i en specifik extrem miljö - människan. READ MORE

  4. 4. Development of Gene Therapy for Hematopoietic Stem Cells using Lentiviral Vectors

    University dissertation from Margareta Ingloff (Secretary) Dept. of Molecular Medicine & Gene Therapy, BMC A12, SE-22184 Lund, Sweden, tel. +46 46 222-0575

    Author : Niels-Bjarne Woods; Lunds universitet.; Lund University.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cell; Hematopoietic stem cell; lentiviral vector; transduction efficiency; transgene expression; multiple vector copy integration; insertional mutagenesis; NOD SCID mouse; cytogenetics; Genetics; extracellulära vätskor; extracellular fluids; cytogenetik; Genetik; Haematology; Hematologi;

    Abstract : Hematopoietic stem cells are an ideal target for genetic manipulation for the purpose of curing hematological disorders as they have the ability to develop into all blood lineages and to self-renew. In this study we demonstrate that lentiviral vectors, based on HIV-1, can efficiently transfer genes into human hematopoietic progenitor and stem cells as assessed following stem cell transplantation in immune compromised mice. READ MORE

  5. 5. Gene expression in carcinogenesis

    University dissertation from Stockholm : Karolinska Institutet, Department of Molecular Medicine

    Author : Heléne Fischer; Karolinska Institutet.; Karolinska Institutet.; [2001]

    Abstract : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. READ MORE