Search for dissertations about: "extracellulära vätskor"

Showing result 1 - 5 of 55 swedish dissertations containing the words extracellulära vätskor.

  1. 1. Expression and role of the cytokine tyrosine kinase receptor flt3 in early hematopoiesis

    University dissertation from Jörgen Adolfsson, Stem Cell Laboratory, BMC B10, Klinikg 26, 22184 Lund

    Author : Jörgen Adolfsson; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; flt3; cytokine; Hematopoiesis; stem cells;

    Abstract : Mature blood cells are crucial for life, but they have a short lifetime and thus have to be replaced. These mature blood cells are produced by lineage restricted progenitors, which themselves are generated by rare multipotent hematopoietic stem cells (HSCs) in a highly dynamic process called hematopoiesis. READ MORE

  2. 2. Gene Expression Studies of Hematologic Malignacies

    University dissertation from Divison of Clinical Genetics

    Author : Anna Andersson; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; cancer; onkologi; Cytologi; oncology; Cytology; acute myeloid leukemia; acute lymphoblastic leukemia; normal hematopoietic cells; cDNA microarray; gene expression profiling; hematopoiesis; pediatric leukemia; fusion gene; Pediatrics; Pediatri; Clinical genetics; Klinisk genetik; cancerology; Hematologi; extracellulära vätskor;

    Abstract : The general aim of this thesis was to characterize hematologic malignancies using gene expression profiling in order to obtain an improved classification and to study deregulated transcriptional networks in leukemia. In the first study (Article I), the gene expression profiles of hematologic cell lines were analyzed to investigate whether such cell lines maintain expression profiles that are characteristic of their primary genetic changes. READ MORE

  3. 3. Towards Gene Therapy of Osteopetrosis

    University dissertation from Department of Molecular Medicine and Gene Therapy, Lund University

    Author : Maria Askmyr; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Haematology; oc oc mice; osteoclast; hematopoietic stem cells; Hematologi; extracellulära vätskor;

    Abstract : The goal in this thesis is development of gene therapy for malignant infantile osteopetrosis (IMO), a rare but severe genetic bone disease. The concept of osteopetrosis implies dysfunction or lack of osteoclasts, the bone resorbing cells in our body, resulting in failure of normal bone breakdown. READ MORE

  4. 4. Membrane traffic in neutrophils and neutrophil-like cells

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Susanne Bauer; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; membrane traffic; Hematologi; extracellular fluids; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; CD177; extracellulära vätskor; PR3; phagocytosis; Streptococcus pyogenes; Infektioner; neutrophils;

    Abstract : The neutrophil constitutes the first line of defence against invading organisms and its primary function is to recognize, phagocytose and kill intruding microorganisms. In this thesis, the membrane traffic in neutrophils and neutrophil-like cells was studied. Non-opsonised S. READ MORE

  5. 5. On the role of the retinoblastoma tumor suppressor gene in hematopoietic differentiation

    University dissertation from Gösta Bergh, Kävlingev 1, S-222 40 Lund, Sweden

    Author : Gösta Bergh; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antisense; leukemia; cell cycle; differentiation; hematopoiesis; p16; p53; tumor suppressor genes; RB; oligonucleotides; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : The aim of this study was to investigate the role of some tumor suppressor gene products (with emphasis on the retinoblastoma suppressor gene product) in the regulation of differentiation and proliferation in leukemic and normal hematopoietic cells. For this purpose, the expression of the tumor suppressor genes RB, p53 and p16 were artificially altered. READ MORE