Search for dissertations about: "extracellular histones extracellular DNA"

Found 5 swedish dissertations containing the words extracellular histones extracellular DNA.

  1. 1. The release of histone proteins from cells via extracellular vesicles

    University dissertation from Umeå : Umeå University

    Author : Uma Muthukrishnan; Umeå universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

    Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE

  2. 2. Complement in Autoimmunity - the importance of clearing waste

    University dissertation from Protein Chemistry, Lund University

    Author : Jonatan Leffler; Lunds universitet.; Lund University.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; annexins; apoptosis; Complement system; neutrophil extracellular traps; systemic lupus erythematosus; C1q; factor H; histones;

    Abstract : Popular Abstract in Swedish Varje dag dör miljoner celler i kroppen. Döda celler som finns kvar i kroppen innehåller ämnen som kan reta immunförsvaret och skapa inflammationer. Därför är det viktigt att döda celler tas om hand av kroppen på ett sådant sätt att inte immunförsvaret aktiveras. READ MORE

  3. 3. On dysregulated inflammation and airway host defense

    University dissertation from Lund University, Faculty of Medicine

    Author : Ravi K. V. Bhongir; Lunds universitet.; Lund University.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aiway inflammation; Chronic obstructive pulmonary disease COPD ; Cystic Fibrosis; Pseudomonas aeruginosa; DNase I;

    Abstract : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. READ MORE

  4. 4. Platelets – Multifaceted players in tumor progression and vascular function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Yanyu Zhang; Uppsala universitet.; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. READ MORE

  5. 5. Characterizing phenotypes of Mycobacterium tuberculosis and exploring anti-mycobacterial compounds through high content screening

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Sadaf Kalsum; Linköpings universitet.; Linköpings universitet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Tuberculosis (TB), an airborne disease and one of the top 10 causes of death globally, is caused by Mycobacterium tuberculosis (Mtb). Current standard therapy for TB treatment includes multiple drugs for a period of at least 6 months. READ MORE