Advanced search

Showing result 1 - 5 of 592 swedish dissertations matching the above criteria.

2. 1. The release of histone proteins from cells via extracellular vesicles

   Author : Uma Muthukrishnan; Jonathan Gilthorpe; Miles Trupp; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

   Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE

4. 2. Proteins of the Inter-α-inhibitor Family : Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components

   Author : Aneta Kaczmarczyk; Erik Fries; Anders Malmström; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; bikunin; inter-α-inhibitor; pre-α-inhibitor; intracellular processing; plasma clearance; extracellular matrix; binding; collagen; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Abstract : Bikunin, a chondroitin sulfate-containing protein of 25 kDa, has protease inhibitory activity and occurs in the plasma in free and complexed form. In inter-α-inhibitor (IαI) and pre-a-inhibitor (PαI) it is covalently linked through its chondroitin sulfate (CS) chain to two or one other polypeptide of about 80 kDa – heavy chains 1 and 2 (H1, H2) and heavy chain 3 (H3) – respectively. READ MORE

5. 3. Studies on extracellular matrix proteins in vascular disease

   Author : Åsa Ström; Kärlväggsbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kardiovaskulära systemet; Cardiovascular system; smooth muscle cells; osteopontin; extracellular matrix; atherosclerosis;

   Abstract : The composition of the vascular extracellular matrix (ECM) is altered during remodeling conditions such as atherosclerosis. The changed ECM regulates events that are important for the progression of disease including smooth muscle cell (SMC) behaviour and collagen fiber formation. READ MORE

6. 4. Advanced Fluorescence Microscopy to Study Plasma Membrane Protein Dynamics

   Author : Joachim Piguet; Horst Vogel; Ruud Hovius; Jerker Widengren; Antoine Triller; Switzerland Ecole Polytechnique Fédérale de Lausanne (EPFL); []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fluorescence; microscopy; plasma membrane; membrane proteins; membrane proteins diffusion; single-molecule imaging; single-molecule tracking; pentameric ligand-gated ion channels; nicotinic acetylcholine receptor; serotonin receptor; synapse; neuromuscular junction; post-synaptic scaffold; rapsyn; myopathies; fluorescent proteins; Förster resonance energy transfer; FRET imaging; protein-protein interactions; protein trafficking; photo-activatable proteins; Biological Physics; Biologisk fysik;

   Abstract : Membrane protein dynamics is of great importance for living organisms. The precise localization of proteins composing a synapse on the membrane facing a nerve terminus is essential for proper functioning of the nervous system. In muscle fibers, the nicotinic acetylcholine is densely packed under the motor nerve termini. READ MORE

7. 5. Enzymatic treatment of wastewater sludge. Sludge solubilisation, improvement of anaerobic digestion and extraction of extracellular polymeric substances

   Author : Joanna Wawrzynczyk; Tillämpad biokemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; pollution control; Environmental technology; sludge treatment; wastewater activated sludge; Proteins; enzymology; Proteiner; enzymologi; cation-binding agents; mass reduction; lectins; extracellular polymeric substances; enzymes; enzymatic activity; anaerobic digestion; biogas; Miljöteknik; kontroll av utsläpp; Biotechnology; Bioteknik;

   Abstract : The processing and disposal of sludge from wastewater treatment plants is an important topic of increasing environmental, ecological, technological, economic and social concern. The large amounts of sludge produced represent an urgent problem today, new treatment methods being very much needed. READ MORE