Search for dissertations about: "extracellular release"

Showing result 11 - 15 of 266 swedish dissertations containing the words extracellular release.

  2. 11. Vesicle-independent extracellular release and bioactivity of peptidoglycan-associated lipoprotein from Aggregatibacter actinomycetemcomitans

    Author : Maribasappa Karched; Sirkka Asikainen; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peptidoglycan-associated lipoprotein; outer membrane proteins; immunoproteomics; periodontitis; cytokines; Aggregatibacter actinomycetemcomitans.; Oral microbiology; Oral mikrobiologi;

    Abstract : Aggregatibacter (Actinobacillus) actinomycetemcomitans is a Gram-negative coccobacillus of the Pasteurellaceae family. It is implicated in periodontitis, a common low-grade bacterial infection, but it can also cause non-oral infections. The main aim of this project was to identify and characterize in A. READ MORE

  4. 12. Functional Aspects of the Juxtaglomerular Apparatus : Control of Glomerular Filtration and Renin Release

    Author : Johan Sällström; Erik Persson; Peter Hansell; Jürgen Schnermann; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The juxtaglomerular apparatus (JGA) is a control unit of the kidney, that regulates glomerular filtration rate (GFR) and renin release, and hence extracellular volume and blood pressure. The tubuloglomerular feedback (TGF) mechanism is a negative feedback loop that regulates GFR. READ MORE

  5. 13. Preterm intraventricular haemorrhage - Effects of extracellular haemoglobin

    Author : Snjolaug Sveinsdottir; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Intraventricular haemorrhage (IVH) is the most common brain lesion in preterm infants and is most commonly seen in the sickest children, with 15-20% of very preterm infants developing IVH. The mortality of infants with severe IVH is 20-50 % in the neonatal period and over 50 % of surviving infants develop post-haemorrhagic ventricular dilatation (PHVD) and 40-80 % develop severe neurological impairment, mainly cerebral palsy and mental retardation. READ MORE

  6. 14. Mechanistic studies on the role of extracellular vesicles in the tumor microenvironment

    Author : Helena Christianson; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microvesicle; exosome; Key words Extracellular vesicle; glioblastoma; hypoxia; angiogenesis; acidosis; proteoglycan; endocytosis; carbonic anhydrase IX; biomarker.;

    Abstract : The transition from normal into malignant cells with acquired uncontrolled growth is a process where cancer cells viciously develop adaptive strategies to overcome microenvironmental and metabolic stress. Hypoxia, or deficient oxygen supply, is a common feature of the expanding tumor which alters cell metabolism and consecutively causes lowered intracellular pH. READ MORE

  7. 15. Analytical Approaches to Study Vesicular and Exosomal Release

    Author : Kim Long Le Vo; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Vesicles, as a special type of entity nanometers in size, are crucial for survival of multicellular organisms. Intracellular vesicles mainly contain specific signaling molecules, transmitters, and modulators whereas extracellular vesicles (EVs) are bioactive organelles carrying a wide range of proteins, genetic materials, and other molecules. READ MORE