Search for dissertations about: "extrinsic factors"

Showing result 1 - 5 of 98 swedish dissertations containing the words extrinsic factors.

  2. 1. Intrinsic and extrinsic factors controlling the differentiation of human midbrain progenitor cells

    Author : Nicolaj Christophersen; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; neurotrophic factors; Parkinson s disease; microarray; dopaminergic; Embryonic stem cells; neural stem cells;

    Abstract : Parkinson's disease (PD) is a common neurodegenerative disorder characterized by motor deficits. Levodopa treatment provides marked symptomatic relief. However, within 5-10 years after the start of Levodopa treatment, most PD patients display a gradual loss of drug efficacy. READ MORE

  4. 2. Amyloid beta aggregation kinetics : The role of intrinsic and extrinsic factors

    Author : Xiaoting Yang; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Alzheimer s disease; Abeta; aggregation; kinetics; secondary nucleation;

    Abstract : Cerebral senile plaque is one of the main pathologies of Alzheimer's disease (AD). The amyloid cascade hypothesis suggests that the aggregation of amyloid beta (Abeta) peptide is involved in the pathogenesis of AD, which is supported by the fact that Abeta overexpression or production of more aggregation-prone variants lead to early-onset dementia. READ MORE

  5. 3. Influence of extrinsic factors on bone scintigraphy an experimental and clinical study

    Author : Marika Cronhjort; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bone scintigraphy; bisphosphonates; biodistribution; animal;

    Abstract : Bone scintigraphy takes advantage of the strong affinity of technetiated diphosphonates to bone. These compounds accumulate particularly at sites of new bone formation which occurs as a response to various conditions affecting bone. READ MORE

  6. 4. Role of transcription factors in sensory neuron specification

    Author : Andreas Montelius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The interface between our mind and the internal and external environments is the peripheral nervous system. A range of different sensory neuron subtypes detects cold, heat, pain, touch, and other stimuli. READ MORE

  7. 5. Tibia stress fractures in athletes : an investigation of possible predisposing factors

    Author : Ingrid Ekenman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Stress fracture; tibia; overuse injuries; biomechanics; strain; trait characteristics; running; exercise dependency; type A behavior; intrinsic factors; extrinsic factors; local deformation; in vivo; sports; muscle; anatomy.;

    Abstract : This study indicated that posteromedial and anterior tibia stress fractures are two entities with different etiology, pathoanatomy and natural course. In both cases clinical examination and bone scintigram were conclusive for the diagnosis. READ MORE