Search for dissertations about: "factor XII"
Showing result 1 - 5 of 12 swedish dissertations containing the words factor XII.
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1. Biomarkers and risk of intracerebral hemorrhage : population-based studies in northern Sweden
Abstract : BackgroundIntracerebral hemorrhage (ICH) is a disease associated with a high morbidity and mortality and treatment options for the condition are limited. Even though an ICH event usually comes as a surprise to the affected individual, pathogenetic processes often have occurred before the sudden ICH event and may have preceded disease onset by years. READ MORE
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2. The Plasma Contact System : New Functional Insights from a Hemostatic and Thrombotic Perspective
Abstract : The physiological role of the plasma contact system still remains a partial enigma. The aim of the presented work was to expand our understanding of the plasma contact system, focusing on its physiological activation and function, principally from a hemostatic perspective. It also explored contact system activation under pathological conditions. READ MORE
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3. Mechanisms and regulation of the polyphosphate/factor XII-driven contact system in thrombosis and hemostasis
Abstract : Blood coagulation leading to fibrin formation is essential to prevent loss of blood (hemostasis), but can also contribute to occlusion of vessels (thrombosis). Thrombosis causes pulmonary embolism, myocardial infarction and stroke, which are together the most common cause of death in the developed world. READ MORE
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4. Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases
Abstract : Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions. READ MORE
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5. The role of platelets in whole blood coagulation
Abstract : The body's first line of defence against bleeding is the platelets, small cell fragments with multiple roles in the coagulation process. The platelets are patrolling our blood vessels, looking for damage in the endothelial cell layer, to which they attach and transform, recruit more platelets and assemble the plasma coagulation proteases on their surfaces. READ MORE