Search for dissertations about: "factor Xa"
Showing result 1 - 5 of 15 swedish dissertations containing the words factor Xa.
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1. Pro- and anticoagulant activities of factor V
Abstract : Coagulation factor V (FV) is activated by thrombin through proteolytic cleavage at Arg-709, Arg-1018 and Arg-1545. Upon thrombin activation, the active form of factor V (FVa) is formed. FVa functions as a cofactor to factor Xa in the conversion of prothrombin to thrombin during coagulation. READ MORE
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2. Structural and functional studies of factor V in health and disease
Abstract : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. READ MORE
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3. Tissue Factor in Complex : Studies of interactions between blood coagulation proteins
Abstract : Many biological processes rely on specific protein-protein interactions, for example immune responses, cell signaling, transcription, and blood coagulation. Blood coagulation is initiated when a vessel wall is damaged, exposing tissue factor (TF) to the circulating factor VII/factor VIIa (FVII/FVIIa) which results in the formation of the TF:FVIIa complex and thereby the initiation of blood coagulation. READ MORE
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4. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions
Abstract : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. READ MORE
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5. The regulation of factor Va activity by activated protein C -Importance of the individual activated protein C cleavage sites in factor Va
Abstract : The subject of this thesis is the activated protein C (APC)-mediated inactivation of factor Va. The activated form of factor V (FVa) is a procoagulant cofactor for Factor Xa (FXa) in the conversion of prothrombin to thrombin. READ MORE