Search for dissertations about: "factories"

Showing result 1 - 5 of 121 swedish dissertations containing the word factories.

  2. 1. Next generation tools for microbial cell factories

    Author : Alister James Cumming; Daniel Daley; Neil Dixon; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbial cell factories; Recombinant protein production; Bacteria; Plasmid; Genetic sensor; Inducible promoter; Genetic cassette; biokemi; Biochemistry;

    Abstract : The bacterium E. coli is a popular choice for expressing recombinant proteins. It is easy to culture and many molecular tools for are available for directing protein production. When producing recombinant proteins, high yields and good quality soluble products are desirable. READ MORE

  4. 2. Droplet microfluidics for screening and sorting of microbial cell factories

    Author : Sara Björk; Helene Svahn Andersson; Håkan Jönsson; Christoph Merten; KTH; []
    Keywords : Droplet microfluidics; Cell factories; High-throughput screening; Cell culture; Bioteknologi; Biotechnology;

    Abstract : Cell factories are cells that have been engineered to produce a compound of interest, ranging from biopharmaceuticals to biofuels. With advances in metabolic engineering, the number of cell factory variants to evaluate has increased dramatically, necessitating screening methods with increased throughput. READ MORE

  5. 3. Plants as Factories for Insect Pheromone Production : Deciphering and Reconstructing Sex Pheromone Biosynthetic Pathways of Female Moths

    Author : Yihan Xia; Funktionell zoologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Pheromones biosynthesis; desaturases; elongases; reductases; plant factories;

    Abstract : Compared to other organisms in which the fatty acyl desaturases (FADs) are mostly involved in normal cellular lipid metabolism, moth FADs have evolved extent functions in the biosynthesis of sex pheromones. Female moths releasespecies-specific sex pheromones to attract conspecific males over a long distance for mating. READ MORE

  6. 4. Engineering microbial cell factories for protein production

    Author : Kiavash Mirzadeh; Daniel Daley; Grzegorz Kudla; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein production; expression vector; recombinant DNA; Translation initiation region; Escherichia coli; mRNA secondary structure; Synthetic evolution; Biochemistry; biokemi;

    Abstract : Proteins are often produced using microbial cell factories for academic or industrial purposes. Protein production is however not an open-and-shut procedure. Production yields often vary in an unpredictable and context dependent manner, limiting the rational design of a straightforward production experiment. READ MORE

  7. 5. Systems Biology of the Secondary Metabolism in Filamentous Fungi

    Author : Jens Christian Froslev Nielsen; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genomics; systems biology; secondary metabolites; antibiotics; Next-generation sequencing; secondary metabolism; filamentous fungi; cell factories; Penicillium;

    Abstract : Filamentous fungi constitute a rich reservoir of pharmaceutically relevant bioactive small molecules. These compounds, commonly referred to as secondary metabolites, are widely used as antibiotics for the treatment of microbial infections, but also as other pharmaceuticals such as immunosuppressors, cholesterol lowering agents and anticancer drugs. READ MORE