Search for dissertations about: "fed-batch control"

Showing result 1 - 5 of 25 swedish dissertations containing the words fed-batch control.

  1. 1. Perturbation-based Control of Industrial Fed-batch Bioprocesses

    University dissertation from Department of Automatic Control, Lund Institute of Technology, Lund University

    Author : Ola Johnsson; Lund University.; Lunds universitet.; [2015]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; perturbation-based control; process control; fed-batch control; industrial bioprocesses;

    Abstract : The topic of this thesis is bioprocess control, more specifically control of industrial-scale microbial fed-batch bioprocesses. Its focus is therefore on methods which are easy to implement in an industrial setting, which gives certain limitations on sensors, actuators and control systems. READ MORE

  2. 2. Probing Control : Analysis and Design with Application to Fed-Batch Bioreactors

    University dissertation from Department of Automatic Control, Lund Institute of Technology, Lund University

    Author : Stéphane Velut; Lund University.; Lunds universitet.; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Elektronik och elektroteknik; Electronics and Electrical technology; Large scale fermentations; Extremum control; Feeding strategy; Probing control; Fed-batch bioreactors; Automation; robotics; control engineering; Automatiska system; robotteknik; reglerteknik;

    Abstract : In most control problems the objective is to control the output at a desired value in spite of disturbances. In some cases, the best setpoint is not known a priori and it should be found online to optimize the process performance. This thesis examines a probing strategy that can be applied for this class of problems. READ MORE

  3. 3. Feeding Strategies Based on Probing Control for E. coli and V. cholerae Cultivations

    University dissertation from Department of Automatic Control, Lund Institute of Technology, Lund University

    Author : Lena de Maré; Lund University.; Lunds universitet.; [2006]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; robotics; control engineering; Automatiska system; robotteknik; reglerteknik; Automation; Temperature; Mid-ranging control; Amino acid; Complex media; Fed-batch bioreactors; Probing control; Biotechnology; Bioteknik; Parameter estimation; Feeding strategies;

    Abstract : The recombinant DNA techniques have made it possible to produce many different proteins for a wide range of applications. The vector encoding for the recombinant protein is often inserted in the bacterium E. coli as it is a well studied and a well-known organism. To achieve a high productivity, it is important to reach a high cell density. READ MORE

  4. 4. Probing Control of Glucose Feeding in Escherichia coli Cultivations

    University dissertation from Department of Automatic Control, Lund Institute of Technology (LTH)

    Author : Mats Åkesson; Lund University.; Lunds universitet.; [1999]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Automatiska system; control engineering; robotics; Automation; dissolved oxygen; acetate; glucose feeding; robotteknik; Escherichia coli; Process control; fed-batch cultivation; reglerteknik; Biotechnology; Bioteknik;

    Abstract : Production of many proteins can today be made using genetically modified organisms. One of the most frequently used host organisms is the bacterium Escherichia coli. A difficulty encountered in cultivations of E. coli is the accumulation of the metabolic by-product acetate which inhibits cell growth and production of a desired protein. READ MORE

  5. 5. Performance and Scale-up of Escherichia coli Fed-batch Processes- Oxygenation of the Human Growth Hormone Process

    University dissertation from Stockholm : Bioteknologi

    Author : Andreas Castan; KTH.; [2001]
    Keywords : E. coli; fed-batch; DO-control; oxygen transfer; cell lysis; DNA release; mixed acid fermentation; formate formation; oxygen enriched air supply; flow cytometry; recombinant human growth hormone rhGH ;

    Abstract : .... READ MORE