Search for dissertations about: "felodipine thesis"

Showing result 1 - 5 of 8 swedish dissertations containing the words felodipine thesis.

  2. 1. Metabolism of felodipine : mechanistic and kinetic studies in vitro - in vivo correlations

    Author : Catharina Bäärnhielm; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  4. 2. Metabolism of felodipine : analytical methods for qualitative and quantitative studies

    Author : Lars Weidolf; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  5. 3. Lecithin-Based Microemulsions for Pharmaceutical use - Phase behavior and Solution Structure

    Author : Christian von Corswant; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; felodipine; solubilization; drug delivery; self-diffusion NMR; alkylmaltoside; microstructure; isopropyl myristate; triglyceride; soybean phosphatidylcholine; Microemulsion; lecithin; Livsmedelsteknik;

    Abstract : Microemulsions are thermodynamically stable, transparent solutions of water, oil and amphiphile(s). It is possible to incorporate large amounts of oil in microemulsions, which makes them interesting for use as a drug delivery vehicle for water insoluble drugs. A prerequisite for pharmaceutical use, however, is a low toxicity of the composition. READ MORE

  6. 4. Cardiovascular and sympatho-adrenal responses to mental stress with special reference to the regulation of human forearm blood flow

    Author : Madeleine Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adrenaline; axillary blockade; beta-receptor blockader; calcium channel blockers; cholinergic blockingagents; felodipine; hypertension-primary; noradrenaline; skeletal muscle; sodium nitroprusside; stress-psychologicai; vascular resistance;

    Abstract : The cardiovascular and sympatho-adrenal responses to a standardized mental stress test (Stroop's colour word conflict test CWT) were studied in 63 healthy and 11 hypertensive men by intraarterial pressure measurements, forearm blood flow by occlusion plethysmography and noradrenaline (NA) and adrenaline (ADR) determinations in arterial and venous plasma. One study included central hemodynamics by right heart catheterization and NA turnover by an isotope dilution method, permitting studies of NA kinetics in the whole body and in a regional vascular bed (the forearm) in hypertensive patients and age-matched controls. READ MORE

  7. 5. Application of Mixed-Effect Modeling to Improve Mechanistic Understanding and Predictability of Oral Absorption

    Author : Martin Bergstrand; Mats O Karlsson; Hans Ericsson; Bart Ploeger; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Absorption; magnetic marker monitoring; drug release; IVIVC; pharmacometrics; NONMEM; model diagnostics; pcVPC; pvcVPC; visual predictive check; VPC; BQL; paracetamol; sulfapyridine.; Other pharmacy; Övrig farmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Abstract : Several sophisticated techniques to study in vivo GI transit and regional absorption of pharmaceuticals are available and increasingly used. Examples of such methods are Magnetic Marker Monitoring (MMM) and local drug administration with remotely operated capsules. READ MORE