Search for dissertations about: "felveckade proteiner"

Showing result 1 - 5 of 7 swedish dissertations containing the words felveckade proteiner.

  1. 1. Analytical Approaches to Neurodegenerative Disease Protein Aggregation

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Henning Wiberg; Åsa Emmer; Torbjörn Gräslund; Leopold Ilag; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurodegenerative diseases; protein misfolding; protein aggregation; gel electrophoresis; isoelectric focusing; immunodetection; ELISA; immunoprecipitation; mass spectrometry; nanoelectrospray; liquid chromatography; neurodegenerativa sjukdomar; felveckade proteiner; proteinaggregering; geleektrofores; isoelektrisk fokusering; immundetektion; ELISA; immunoprecipitering; masspektrometri; nanoelektrospray; vätskekromatografi; NATURAL SCIENCES Chemistry Analytical chemistry; NATURVETENSKAP Kemi Analytisk kemi;

    Abstract : .... READ MORE

  2. 2. Molecular Aspects of Transthyretin Amyloid Disease

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Karin Sörgjerd; Per Hammarström; Joel Buxbaum; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloid; apoptosis; BiP; chaperone; misfolding; oligomer; transthyretin; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi;

    Abstract : This thesis was made to get a deeper understanding of how chaperones interact with unstable, aggregation prone, misfolded proteins involved in human disease. Over the last two decades, there has been much focus on misfolding diseases within the fields of biochemistry and molecular biotechnology research. READ MORE

  3. 3. Amyloid Beta – Biotherapy Target and Biotechnological Tool

    University dissertation from KTH Royal Institute of Technology

    Author : Sebastian W. Meister; Stefan Ståhl; John Löfblom; Maarten Merkx; [2020]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Alzheimer’s disease; amyloid beta; blood-brain barrier; green-fluorescent protein; intracellular assays; proteases; protease substrate specificity; protein aggregation; protein engineering.; Biotechnology; Bioteknologi;

    Abstract : Alzheimer’s disease is a progressive neurodegenerative disease characterized primarily by memory impairment and cognitive decline. As of 2020, an estimated 50 million people suffer from Alzheimer’s disease or related dementia and no disease-modifying treatment options are yet approved for clinical practice. READ MORE

  4. 4. Combined structural methods to characterize an oligomeric small heat shock protein Hsp21

    University dissertation from Lund University, Faculty of Science, Department of Chemistry, Division of Biochemistry and Structural Biology

    Author : Gudrun Rutsdottir; [2017-05]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Small heat shock proteins; chaperones; crosslinking mass spectrometry; Stable isotope labeling; quantification; small angle X-ray scattering; cryo-electron microscopy; combined structural methods; plant stress;

    Abstract : Small heat shock proteins (sHsps) are found in all organisms and evolved early in the history of life, prior to the divergence of the three domains of life (Archaea, Bacteria, and Eukarya). Their malfunction is connected to several different diseases in humans, such as Alzheimer’s and Parkinson’s disease. READ MORE

  5. 5. Peptide folding and local unfolding of SOD1 in the presence of interacting macromolecular crowders - a Monte Carlo approach

    University dissertation from Lund University, Faculty of Science, Department of Astronomy and Theoretical Physics

    Author : Anna Bille; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Monte Carlo simulations; protein folding; SOD1; crowding; Fysicumarkivet A:2016:Bille;

    Abstract : A protein chain often folds into a functional, specific three dimensional structure. Failurein this process can in some cases lead to disease, e.g. the misfolding disease ALS. READ MORE