Search for dissertations about: "fetal kidney"

Showing result 16 - 20 of 28 swedish dissertations containing the words fetal kidney.

  2. 16. Nephroprotective effect of the cardiotonic steroid ouabain

    Author : Ievgeniia Burlaka; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : It has been shown that Na,K-ATPase (NKA) is a signal transducer. Our group described the anti-apoptotic effect of ouabain to the signaling function of NKA. READ MORE

  4. 17. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism : Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

    Author : Kerstin Lundell; Kjell Wikvall; Ronnie Hansson; Stefan Alexson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Abstract : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. READ MORE

  5. 18. Data integration and visualization in type 2 diabetes research and care: From biological mechanisms to precision medicine

    Author : Olof Asplund; diabetes och endokrinologi Genomik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type 2 diabetes T2D ; human pancreatic islets; human skeletal muscle; transcriptomics; genomics; phenomics; ANDIS; diabetes; diabetics;

    Abstract : Background. Type 2 diabetes (T2D) is a complex heterogeneous disorder affecting multiple organs. Gene expression studies in organs central to T2D, such as pancreatic islets and skeletal muscle will help elucidate and disentangle molecular mechanisms underlying T2D. READ MORE

  6. 19. New predictive and diagnostic biomarkers for preeclampsia

    Author : Ulrik Dolberg Anderson; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Abstract Preeclampsia is a serious pregnancy complication that affects 3-8% of all pregnancies leading to maternal- and fetal morbidity and mortality. The etiology is still not known in detail. Previous findings have shown an up regulation of the genes coding for fetal hemoglobin (HbF) in preeclamptic placentas. READ MORE

  7. 20. Primary structure, expression and function of laminin [alpha]4

    Author : Jarkko Kortesmaa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Basement membranes (BMs) are thin extracellular sheet-like structures that compartmentalize tissues. They are found beneath epithelia and endothelia, and surrounding individual cells, such as muscle fibers, neurons and adipocytes. Laminins, type IV collagens, perlecan and nidogens are some of the main components of mature basement membranes. READ MORE