Search for dissertations about: "fetal rat liver"

Showing result 11 - 14 of 14 swedish dissertations containing the words fetal rat liver.

2. 11. CYP2W1 in colorectal cancer : aspects of risk, prognosis and future treatment options

   Author : Kristina Stenstedt; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Colorectal cancer (CRC) is a common disease and a major cause of cancer related death globally. Prognosis is rather good in early stages but worse in cases with disseminated disease. There is a constant need of developing all treatment modalities, which also has been done over the last decades. READ MORE

4. 12. Molecular studies of the insulin-like growth factor system in the brain : focus on growth, tumorigenesis and trauma

   Author : Ann-Christin Sandberg Nordqvist; Karolinska Institutet; Karolinska Institutet; []
   Keywords : insulin-like growth factors; insulin-like growth factor binding proteins; brain; mRNA; meningioma; glioma; traumatic brain injury; in situ hybridization; Northern blothybridization;

   Abstract : Insulin-like growth factor (IGF) 1 and -2 are synthesized by most tissues of the body and function as autocrine or paracrine agents in a tissue-specific manner. mRNA for IGF-1 and -2, as well as the IGF-binding proteins, are synthesized locally in various regions of the brain. READ MORE

5. 13. Epigenic regulation and posttranslational modification of human cytochrome P450s : focus on CYP2W1, CYP1A2 and CYP2C18

   Author : Alvin V Gomez; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The cytochrome P450 superfamily represents a very important group of enzymes that are responsible for the metabolism of drugs as well as of endogenous compounds. Many P450s are genetically polymorphic causing important interindividual variability in P450 expression and activity whereas in some cases the basis for interindividual variation has still not been resolved. READ MORE

6. 14. Murine plasmacytomagenesis : an experimental model of B-cell neoplasia

   Author : Santiago C Silva; Karolinska Institutet; Karolinska Institutet; []
   Keywords : mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

   Abstract : A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Lymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. READ MORE