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Found 5 swedish dissertations matching the above criteria.

2. 1. Metabolic consequences of a Paleolithic diet in obese postmenopausal women

   Author : Caroline Blomquist; Tommy Olsson; Elin Chorell; Per-Arne Svensson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Postmenopausal women; Paleolithic diet; randomized diet intervention; fat metabolism; low-grade inflammation; circulating fatty acids; diet validation; obesity; insulin resistance; Postmenopausala kvinnor; Paleolitisk kost; randomiserad kostintervention; fettmetabolism; fetma; låggradig inflammation; cirkulerande fettsyror; kostvalidering; fetma; insulin resistens; medicin; Medicine;

   Abstract : BackgroundObesity, in particular abdominal adiposity, is associated with elevated fatty acids and pro-inflammatory adipokines, which are linked to ectopic fat storage and insulin resistance. During menopause, there is a redistribution of fat from the peripheral to abdominal depots. READ MORE

4. 2. Discovery of Novel Receptors for Lipid Mediators - a study leading to the identification of receptors involved in metabolism and the immune system

   Author : Niclas Nilsson; Institutionen för experimentell medicinsk vetenskap; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; Thiazolidinedione; SCFA; FFA; FFA2R; FFA1R; GPR43; GPR41; GPR40; BLT2; GPCR; Orphan; Receptor;

   Abstract : Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. READ MORE

5. 3. ALPHA-LINOLENIC ACID Postprandial Lipid Metabolism and Enzymatic Interesterification of Triacylgylcerols

   Author : Julia Svensson; Bioteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; alpha-linolenic acid; triacylglycerol; postprandial lipemia; Lipozyme TL IM; interesterification;

   Abstract : An important indicator of the metabolic capacity of humans is the ability to regulate plasma triacylglycerol levels and to clear triacylglycerol-rich lipoproteins (TRLs) from the circulation after a meal. This is crucial since most of the day is spent in the postprandial state. READ MORE

6. 4. Exploring the Grey Zone between Type 1 and Type 2 Diabetes

   Author : Ekaterine Bakhtadze; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring at least for 6 month after diagnosis. READ MORE

7. 5. Experimental Traumatic Brain Injury and Cell Death - in vivo and in vitro aspects

   Author : Gustav Mattiasson; Sektion IV; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofysiologi; neuropsychology; Neurology; uncoupling protein; mitochondrial permeability transition; cerebral blood flow; functional outcome; cell death; mitochondria; hippocampus; preconditioning; trauma; Brain; ischemia; neuropsykologi; Neurologi; neurophysiology;

   Abstract : Traumatic and ischemic brain damage are major causes of disability and death. While much effort has been spent on developing pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. READ MORE